Zobrazeno 1 - 3
of 3
pro vyhledávání: '"D T, Manallack"'
Publikováno v:
Journal of computer-aided molecular design. 11(2)
The origins and operation of artificial neural networks are briefly described and their early application to data modelling in drug design is reviewed. Four problems in the use of neural networks in data modelling are discussed, namely overfitting, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b606a4f3a479a3b68521cea983081c6
https://pubmed.ncbi.nlm.nih.gov/9089431
https://pubmed.ncbi.nlm.nih.gov/9089431
Publikováno v:
Arzneimittel-Forschung. 43(10)
The quantitative structure-activity relationships (QSAR's) of 3 series of arylcyclohexylamines have been investigated using computational chemistry and multivariate statistics. Principal component analysis of the aromatic ring data set demonstrated s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2850318b62cf920955788d245498bdb8
https://pubmed.ncbi.nlm.nih.gov/8267664
https://pubmed.ncbi.nlm.nih.gov/8267664
Publikováno v:
Molecular pharmacology. 34(6)
Computer-assisted molecular modelling techniques and electrostatic analyses of a wide range of phenycyclidine (PCP) and sigma ligands, in conjunction with radioreceptor studies, were used to determine the topographies of the PCP and sigma receptors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44423a3f8dbf2a7c58667c6712a841f4
https://pubmed.ncbi.nlm.nih.gov/2849051
https://pubmed.ncbi.nlm.nih.gov/2849051