Zobrazeno 1 - 10 of 34 pro vyhledávání: '"D T, Golenbock"'
1
Dual effects of LPS antibodies on cellular uptake of LPS and LPS-induced proinflammatory functions
Autor: M Pollack, C A Ohl, D T Golenbock, F Di Padova, L M Wahl, N L Koles, G Guelde, B G Monks
Publikováno v: The Journal of Immunology. 159:3519-3530
Human phagocytes recognize bacterial LPS (endotoxin) through membrane CD14 (mCD14), a proinflammatory LPS receptor. This study tested the hypothesis that anti-LPS Abs neutralize endotoxin by blocking cellular uptake through mCD14. Ab-associated chang
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbbaf9163da847aaa18e634edba0bec7
https://doi.org/10.4049/jimmunol.159.7.3519
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2
Outside-in signaling by lipopolysaccharide through a tailless integrin
Autor: R R Ingalls, M A Arnaout, D T Golenbock
Publikováno v: The Journal of Immunology. 159:433-438
Ligand binding to integrins activates intracellular signaling pathways that coordinate and regulate a variety of cellular responses. There is evidence to suggest that the cytoplasmic tails play a key role in several of these signaling events. We soug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d74064cb5a60bc3c715227733aedee66
https://doi.org/10.4049/jimmunol.159.1.433
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3
Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II
Autor: T A Lodie, R Savedra, D T Golenbock, C P Van Beveren, R A Maki, M J Fenton
Publikováno v: The Journal of Immunology. 158:1848-1856
We previously reported that LPS stimulation of the RAW264.7 murine macrophage cell line rapidly induced a structural change within the N terminus of the transcriptional regulatory factor PU.1. PU.1 is required for the expression of a variety of cytok
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6e60004de86c86feedc7d9291d59a91
https://doi.org/10.4049/jimmunol.158.4.1848
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4
Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system
Autor: R Savedra, R L Delude, R R Ingalls, M J Fenton, D T Golenbock
Publikováno v: The Journal of Immunology. 157:2549-2554
Phagocytic leukocytes respond to a variety of bacterial products including Gram-negative bacterial LPS and mycobacterial lipoarabinomannan (LAM). Anti-CD14 mAbs have been shown to block LPS and LAM activation of myeloid cells, suggesting that CD14 is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e41cb9080cfdb08daeff926a4261db89
https://doi.org/10.4049/jimmunol.157.6.2549
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5
Acyclic analogue of lipid A stimulates TNF-alpha and arachidonate release via a unique LPS-signaling pathway
Autor: M A Fagan, Y Liu, P Stütz, H Vyplel, D T Golenbock
Publikováno v: The Journal of Immunology. 153:5230-5238
LPS has been implicated in the pathogenesis of Gram-negative bacterial sepsis. Despite intensive efforts to define the LPS-signal transduction pathway, CD14 is the sole molecule clearly demonstrated to possess signaling capabilities. However, it rema
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a28e6963cc3dea248380ec3918d68221
https://doi.org/10.4049/jimmunol.153.11.5230
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6
MyD88-dependent pathway is essential for the innate immunity to Enterocytozoon bieneusi
Autor: Q, Zhang, X, Feng, W, Nie, D T, Golenbock, H, Mayanja-Kizza, S, Tzipori, H, Feng
Publikováno v: Parasite immunology. 33(4)
Enterocytozoon bieneusi is clinically the most significant microsporidian parasite associated with persistent diarrhoea, wasting and cholangitis in 30-50% of individuals with HIV/AIDS, as well as in malnutritional children and in the recipients of im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5d96b42929b12154aba3070792639c6
https://pubmed.ncbi.nlm.nih.gov/21204848
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7
Lipopolysaccharide-induced stimulation of CD11b/CD18 expression on neutrophils. Evidence of specific receptor-based response and inhibition by lipid A-based antagonists
Autor: W A Lynn, C R Raetz, N Qureshi, D T Golenbock
Publikováno v: The Journal of Immunology. 147:3072-3079
Gram-negative bacterial septicemia is a common clinical syndrome resulting, in part, from the activation of phagocytic leukocytes by LPS. By using flow cytometry, we have characterized LPS-induced expression of the beta 2 integrin CD11b/CD18. After e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f74815ba0bf2cb289ddb6135abf4929
https://doi.org/10.4049/jimmunol.147.9.3072
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10
Differential roles of TLR2 and TLR4 in the host response to Gram-negative bacteria: lessons from a lipopolysaccharide-deficient mutant of Neisseria meningitidis
Autor: R R, Ingalls, E, Lien, D T, Golenbock
Publikováno v: Journal of endotoxin research. 6(5)
The inflammatory response to bacterial infections plays an important role in the detection and elimination of invading micro-organisms. Various components of the bacterial cell wall are capable of activating this pro-inflammatory response. In the cas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7550f8a91c9eeb767cbdcc73b18f478f
https://pubmed.ncbi.nlm.nih.gov/11521065
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