Zobrazeno 1 - 10 of 23 pro vyhledávání: '"D Syrengelas"'
1
Idiotype-encoding recombinant adenoviruses provide protective immunity against murine B-cell lymphomas
Autor: Ronald Levy, Athanasia D. Syrengelas, John M. Timmerman, Stacie L. Lambert, Clemens B. Caspar
Publikováno v: Blood. 97:1370-1377
Vaccination with tumor-specific immunoglobulin or idiotype (Id) is a promising new form of immunotherapy for B-cell malignancies. Id protein vaccination has demonstrated clinical activity in B-cell lymphomas, yet it requires the laborious and time-co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0786af5b6b28530f76d3c102c20a83f5
https://doi.org/10.1182/blood.v97.5.1370
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2
Tumor-Specific Idiotype Vaccines in the Treatment of Patients With B-Cell Lymphoma — Long-Term Results of a Clinical Trial
Autor: Behnaz Taidi-Laskowski, Debra K. Czerwinski, Frank J. Hsu, Larry W. Kwak, Clemens B. Caspar, Tina Marie Liles, Athanasia D. Syrengelas, Ronald Levy
Publikováno v: Blood. 89:3129-3135
The surface Ig on each B-cell lymphoma has unique portions (idiotypes), which can be recognized by the immune system. In this study, we immunized patients against the Ig expressed by their tumor and observed their clinical outcomes. After standard ch
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7aed995535e14a05fa25d89ccfa66d4c
https://doi.org/10.1182/blood.v89.9.3129
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3
DNA immunization induces protective immunity against B–cell lymphoma
Autor: Athanasia D. Syrengelas, Ronald Levy, Thomas T. Chen
Publikováno v: Nature Medicine. 2:1038-1041
Idiotypic determinants of the immunoglobulin expressed on the surface of B-cell lymphomas are tumor-specific antigens (TSAs), which can be targeted by immunotherapy. Immunization with DNA constructs encoding the idiotype (ld) of a murine B-cell lymph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfd2628050201366c204fd5f498d3d5
https://doi.org/10.1038/nm0996-1038
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4
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6
Cytokine Fusion Constructs as DNA Vaccines Against Tumors
Autor: Athanasia D. Syrengelas, Ronald Levy, Holden T. Maecker
Various studies have used DNA vaccination as a method of immunizing against tumors (1-12). As with any tumor vaccine, one challenge is to find a truly tumor-specific antigen (13,14). The majority of immunologically targeted tumor antigens are also ex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b4ab4f4c7b21372824dbebe216e8e81
https://doi.org/10.1385/1-59259-688-6:221
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