Zobrazeno 1 - 10
of 130
pro vyhledávání: '"D Sutcliffe"'
Autor:
Matthew D. Sutcliffe, Philip M. Tan, Antonio Fernandez-Perez, Young-Jae Nam, Nikhil V. Munshi, Jeffrey J. Saucerman
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Direct reprogramming of fibroblasts into cardiomyocytes is a promising approach for cardiac regeneration but still faces challenges in efficiently generating mature cardiomyocytes. Systematic optimization of reprogramming protocols requires
Externí odkaz:
https://doaj.org/article/ed4cfada737b43d2ae2fd966138a9dc7
Autor:
Kevin A. Janes, Hui Zong, Shambhavi Singh, Lauren K. Rosenfeld, Jungeun Kim, Lixin Wang, Rui P. Galvao, Matthew D. Sutcliffe
Cancer evolves from premalignant clones that adopt unusual cell states to achieve transformation. We previously pinpointed the oligodendrocyte precursor cell (OPC) as a cell of origin for glioma, but the early changes of mutant OPCs during premaligna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1068a33aaacd805715bca581c0edaac
https://doi.org/10.1158/0008-5472.c.6513202.v1
https://doi.org/10.1158/0008-5472.c.6513202.v1
Autor:
Kevin A. Janes, Hui Zong, Shambhavi Singh, Lauren K. Rosenfeld, Jungeun Kim, Lixin Wang, Rui P. Galvao, Matthew D. Sutcliffe
Candidate male- and female-specific regulatory heterogeneities in mutant cells at 12 dpi (Sheet 1) and 90 dpi (Sheet 2). Shared candidates are shown as RHEGs for each day.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d15e29932b7d6f364a83d1ba9a58c2
https://doi.org/10.1158/0008-5472.22428976.v1
https://doi.org/10.1158/0008-5472.22428976.v1
Autor:
Kevin A. Janes, Jennifer A. Harvey, Kristen A. Atkins, Kathy Repich, Matthew D. Sutcliffe, Shambhavi Singh
Full METASCAPE analysis of RHEGs organized by gene annotation (Sheet 1), categorical enrichments (Sheet 2), TRRUST candidate regulators (Sheet 3), and predicted enrichments for transcription factor (TF) targets (Sheet 4).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7661ae0a01fee5d906095ea9d500976
https://doi.org/10.1158/0008-5472.22429299
https://doi.org/10.1158/0008-5472.22429299
Autor:
Kevin A. Janes, Hui Zong, Shambhavi Singh, Lauren K. Rosenfeld, Jungeun Kim, Lixin Wang, Rui P. Galvao, Matthew D. Sutcliffe
Supplementary Figures S1-S15, Supplementary Table S1, and captions for Supplementary Files S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877cf9def0e603528bf71ce1b29b5d52
https://doi.org/10.1158/0008-5472.22428985
https://doi.org/10.1158/0008-5472.22428985
Autor:
Kevin A. Janes, Kwon-Sik Park, Matthew D. Sutcliffe, Kee-Beom Kim, Shambhavi Singh, Dylan L. Schaff
Hallmark gene set enrichments for transcripts with human orthologs in MSigDB. Individual worksheets are for SCLC spheroids of KP1-GFP cells (Sheet 1) or Chga-GFP;Rbâ^†/â^†;p53â^†/â^†;p130â^†/+;Crebbp-/- (RPC) cells (Sheet 2) and KP1-GF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1e5eab4daba7d2bbece858012dd947
https://doi.org/10.1158/0008-5472.22428655.v1
https://doi.org/10.1158/0008-5472.22428655.v1
Data from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments
Autor:
Kevin A. Janes, Kwon-Sik Park, Matthew D. Sutcliffe, Kee-Beom Kim, Shambhavi Singh, Dylan L. Schaff
Small-cell lung cancers derive from pulmonary neuroendocrine cells, which have stem-like properties to reprogram into other cell types upon lung injury. It is difficult to uncouple transcriptional plasticity of these transformed cells from genetic ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c08d0fff595b48812e65e1137adf042
https://doi.org/10.1158/0008-5472.c.6513091.v1
https://doi.org/10.1158/0008-5472.c.6513091.v1
Autor:
Kevin A. Janes, Jennifer A. Harvey, Kristen A. Atkins, Kathy Repich, Matthew D. Sutcliffe, Shambhavi Singh
The heterogeneous composition of solid tumors is known to impact disease progression and response to therapy. Malignant cells coexist in different regulatory states that can be accessed transcriptomically by single-cell RNA sequencing, but these meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d1a2855694a9fc88ccd387ccdca8f9d
https://doi.org/10.1158/0008-5472.c.6513306.v1
https://doi.org/10.1158/0008-5472.c.6513306.v1
Autor:
Kevin A. Janes, Jennifer A. Harvey, Kristen A. Atkins, Kathy Repich, Matthew D. Sutcliffe, Shambhavi Singh
Supplementary Figures S1-S12, Supplementary Tables ST1-ST3, and Supplementary File captions S1-S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adda9039ab1f0e67c3cb3059bdd68d2
https://doi.org/10.1158/0008-5472.22429332
https://doi.org/10.1158/0008-5472.22429332
Autor:
Kevin A. Janes, Kwon-Sik Park, Matthew D. Sutcliffe, Kee-Beom Kim, Shambhavi Singh, Dylan L. Schaff
Supplementary Figure S1-S13, Supplementary Table ST1, and captions for Supplementary Files S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5774cf77081e09e6e430443cfb5545
https://doi.org/10.1158/0008-5472.22428661
https://doi.org/10.1158/0008-5472.22428661