Zobrazeno 1 - 10
of 1 337
pro vyhledávání: '"D Stephenson"'
Autor:
Tayleur D. White, Abdulaziz Almutairi, Ying Gai-Tusing, Daniel J. Stephenson, Benjamin D. Stephenson, Charles E. Chalfant, Xiaoyong Lei, Brian Lu, Bruce D. Hammock, Teresa P. DiLorenzo, Sasanka Ramanadham
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWe reported that Ca2+-independent phospholipase A2β (iPLA2β)–derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. As CD4+ and CD8+ T cells are critical in promoting β-cell death, we tested the hypothesis that iDL signalin
Externí odkaz:
https://doaj.org/article/588f970bbb8d45fbb26e60d608d19390
Autor:
T. Kangarloo, R. D. Latzman, J. L. Adams, R. Dorsey, M. Kostrzebski, J. Severson, D. Anderson, F. Horak, D. Stephenson, J. Cosman
Publikováno v:
Frontiers in Digital Health, Vol 6 (2024)
IntroductionDigital health technologies (DHTs) have the potential to alleviate challenges experienced in clinical trials through more objective, naturalistic, and frequent assessments of functioning. However, implementation of DHTs come with their ow
Externí odkaz:
https://doaj.org/article/cc9f195832a94958b3a5f24698a5ae79
Autor:
Elizabeth J. Radford, Hong-Kee Tan, Malin H. L. Andersson, James D. Stephenson, Eugene J. Gardner, Holly Ironfield, Andrew J. Waters, Daniel Gitterman, Sarah Lindsay, Federico Abascal, Iñigo Martincorena, Anna Kolesnik-Taylor, Elise Ng-Cordell, Helen V. Firth, Kate Baker, John R. B. Perry, David J. Adams, Sebastian S. Gerety, Matthew E. Hurles
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Loss-of-function of DDX3X is a leading cause of neurodevelopmental disorders (NDD) in females. DDX3X is also a somatically mutated cancer driver gene proposed to have tumour promoting and suppressing effects. We perform saturation genome edi
Externí odkaz:
https://doaj.org/article/787606f0736b45d2b045e1283e0cd595
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
BackgroundImmune checkpoint inhibitors (ICI) are standard of care therapy for patients with cutaneous malignancies, the most frequently diagnosed cancers in solid organ transplant (SOT) recipients. The activity and rate of allograft rejection in SOT
Externí odkaz:
https://doaj.org/article/476fe1a883574bc08e9b94670c9a6a7d
Autor:
J. Michael Maurer, Keith A. Harenski, Subhadip Paul, Victor M. Vergara, David D. Stephenson, Aparna R. Gullapalli, Nathaniel E. Anderson, Gerard J.B. Clarke, Prashanth K. Nyalakanti, Carla L. Harenski, Jean Decety, Andrew R. Mayer, David B. Arciniegas, Vince D. Calhoun, Todd B. Parrish, Kent A. Kiehl
Publikováno v:
Neuroimage: Reports, Vol 3, Iss 1, Pp 100157- (2023)
Individuals with acute and chronic traumatic brain injury (TBI) are associated with unique white matter (WM) structural abnormalities, including fractional anisotropy (FA) differences. Our research group previously used FA as a feature in a linear su
Externí odkaz:
https://doaj.org/article/21de1cd6e4c44063abc6fcf5afd7d186
Autor:
Andrew R. Mayer, Andrew B. Dodd, Julie G. Rannou-Latella, David D. Stephenson, Rebecca J. Dodd, Josef M. Ling, Carissa J. Mehos, Cidney R. Robertson-Benta, Sharvani Pabbathi Reddy, Rachel E. Kinsler, Meghan S. Vermillion, Andrew P. Gigliotti, Veronik Sicard, Amy L. Lloyd, Erik B. Erhardt, Jessica M. Gill, Chen Lai, Vivian A. Guedes, Irshad H. Chaudry
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-13 (2021)
Abstract Background Traumatic brain injury (TBI) and severe blood loss resulting in hemorrhagic shock (HS) represent leading causes of trauma-induced mortality, especially when co-occurring in pre-hospital settings where standard therapies are not re
Externí odkaz:
https://doaj.org/article/4eb98a8a820c4bd3b173b6aef3f44172
Autor:
Tatiana Popovitchenko, Yongkyu Park, Nicholas F. Page, Xiaobing Luo, Zeljka Krsnik, Yuan Liu, Iva Salamon, Jessica D. Stephenson, Matthew L. Kraushar, Nicole L. Volk, Sejal M. Patel, H. R. Sagara Wijeratne, Diana Li, Kandarp S. Suthar, Aaron Wach, Miao Sun, Sebastian J. Arnold, Wado Akamatsu, Hideyuki Okano, Luc Paillard, Huaye Zhang, Steven Buyske, Ivica Kostovic, Silvia De Rubeis, Ronald P. Hart, Mladen-Roko Rasin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Translational regulation of isoforms in the developing nervous system is not well understood. Here, the authors report translational de-repression of RNA binding protein isoforms at their 5′UTRs in the neocortex and show the neurodevelopmental risk
Externí odkaz:
https://doaj.org/article/26ec0393d8414ff985171a47ea4a1728
Publikováno v:
Geoscientific Model Development, Vol 13, Pp 2031-2050 (2020)
Water mass ventilation provides an important link between the atmosphere and the global ocean circulation. In this study, we present a newly developed, probabilistic tool for offline water mass tracking. In particular, NEMOTAM, the tangent-linear and
Externí odkaz:
https://doaj.org/article/0d5b644a999949adb93c2e6444e1bc87
Autor:
Andrew R. Mayer, Josef M. Ling, Andrew B. Dodd, Julie G. Rannou-Latella, David D. Stephenson, Rebecca J. Dodd, Carissa J. Mehos, Declan A. Patton, D. Kacy Cullen, Victoria E. Johnson, Sharvani Pabbathi Reddy, Cidney R. Robertson-Benta, Andrew P. Gigliotti, Timothy B. Meier, Meghan S. Vermillion, Douglas H. Smith, Rachel Kinsler
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Acceleration parameters have been utilized for the last six decades to investigate pathology in both human and animal models of traumatic brain injury (TBI), design safety equipment, and develop injury thresholds. Previous large animal models have qu
Externí odkaz:
https://doaj.org/article/d7058419edea4d499021b7c30717be2e
Autor:
D. Stephenson, A. Perry, M. R. Appleby, D. Lee, J. Davison, A. Johnston, A. L. Jones, A. Nelson, S. J. Bourke, M. F. Thomas, A. De Soyza, J. L. Lordan, J. Lumb, A. E. Robb, J. R. Samuel, K. E. Walton, J. D. Perry
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background RGM medium is an agar-based, selective culture medium designed for the isolation of nontuberculous mycobacteria (NTM) from the sputum of patients with cystic fibrosis (CF). We evaluated RGM medium for the detection of NTM in patie
Externí odkaz:
https://doaj.org/article/5d1baad6a49e46db891e2a4cb5f5848f