Zobrazeno 1 - 10
of 247
pro vyhledávání: '"D Skelton"'
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Pten, a gene associated with autism spectrum disorder, is an upstream regulator of receptor tyrosine kinase intracellular signaling pathways that mediate extracellular cues to inform cellular development and activity-dependent plasticity. We therefor
Externí odkaz:
https://doaj.org/article/c0ee692b54294944842d4608016b1db8
Publikováno v:
Cells, Vol 11, Iss 1, p 169 (2022)
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease with a similar clinical presentation and progression to idiopathic Parkinson’s disease, and common variation is linked to disease risk. Recapitulation of the genotype in
Externí odkaz:
https://doaj.org/article/98d70a4746ee4da1a208834b5a483f04
Akademický článek
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Akademický článek
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Autor:
Stephanie A. Getz, Kamran Tariq, Dylan H. Marchand, Conor R. Dickson, James R. Howe VI, Patrick D. Skelton, Wei Wang, Meijie Li, Jeremy M. Barry, Jennifer Hong, Bryan W. Luikart
Publikováno v:
J Neurosci
Phosphatase and tensin homolog (PTEN) is a major negative regulator of the phosphatidylinositol-3-kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR) pathway. Loss-of-function mutations inPTENhave been found in a subset of patients with macrocep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecdaad19d297a63518c1c711e80e408
https://doi.org/10.1523/jneurosci.1835-21.2022
https://doi.org/10.1523/jneurosci.1835-21.2022
Autor:
L Swan, F Horgan, V Cummins, F Doyle, R Galvin, E Burton, J Sorensen, S B Jabakhanji, D Skelton, B Townley, D Rooney, G Jackson, L Murphy, A Warters, M O'Sullivan
Publikováno v:
Age and Ageing. 50:i1-i8
Background In Ireland, over 53,000 older adults are supported in their community by formal home support, amounting to an estimated 19 million care hours annually. There is a growing need to move beyond care, to more proactive approaches to maintain p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f22a9cba1b370e31c160e63af7eff93b
https://doi.org/10.1093/ageing/afab216.199
https://doi.org/10.1093/ageing/afab216.199
Autor:
Alyssa M. Ash, Elena Regele-Blasco, Désirée R. Seib, Erin Chahley, Patrick D. Skelton, Bryan W. Luikart, Jason S. Snyder
Publikováno v:
Neurobiology of learning and memory.
Ongoing neurogenesis in the dentate gyrus (DG) subregion of the hippocampus results in a heterogenous population of neurons. Immature adult-born neurons (ABNs) have physiological and anatomical properties that may give them a unique role in learning.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac95a2911b277f365fb4610b323ac7b
https://pubmed.ncbi.nlm.nih.gov/36572174
https://pubmed.ncbi.nlm.nih.gov/36572174
Akademický článek
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Autor:
James R Howe, Emily S Li, Sarah E Streeter, Gilbert J Rahme, Edmond Chipumuro, Grace B Russo, Julia F Litzky, L Benjamin Hills, Kyla R Rodgers, Patrick D Skelton, Bryan W Luikart
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177661 (2017)
Neurogenesis is a highly-regulated process occurring in the dentate gyrus that has been linked to learning, memory, and antidepressant efficacy. MicroRNAs (miRNAs) have been previously shown to play an important role in the regulation of neuronal dev
Externí odkaz:
https://doaj.org/article/2f92d64e147644f3b3aabea259b0e9fc
Autor:
Hyun Ju Cho, Jane D Skelton, Hope S. Rugo, David Weng, Michelle E. Melisko, Timothy J. Pluard, Priyanka Sharma, Koung Eun Yoon, Neelima Vidula
Publikováno v:
Cancer Research. 80:OT1-05
Background: Paclitaxel is a commonly used anticancer drug worldwide for various cancers including breast cancer. DHP107 is a novel oral formulation of lipid based components and paclitaxel. DHP107 showed comparable efficacy and safety to IV paclitaxe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a500c18970c5166e38cb8644db80d919
https://doi.org/10.1158/1538-7445.sabcs19-ot1-05-02
https://doi.org/10.1158/1538-7445.sabcs19-ot1-05-02