Zobrazeno 1 - 10
of 1 382
pro vyhledávání: '"D Schilling"'
Autor:
Alistair T. Pagnamenta, Carme Camps, Edoardo Giacopuzzi, John M. Taylor, Mona Hashim, Eduardo Calpena, Pamela J. Kaisaki, Akiko Hashimoto, Jing Yu, Edward Sanders, Ron Schwessinger, Jim R. Hughes, Gerton Lunter, Helene Dreau, Matteo Ferla, Lukas Lange, Yesim Kesim, Vassilis Ragoussis, Dimitrios V. Vavoulis, Holger Allroggen, Olaf Ansorge, Christian Babbs, Siddharth Banka, Benito Baños-Piñero, David Beeson, Tal Ben-Ami, David L. Bennett, Celeste Bento, Edward Blair, Charlotte Brasch-Andersen, Katherine R. Bull, Holger Cario, Deirdre Cilliers, Valerio Conti, E. Graham Davies, Fatima Dhalla, Beatriz Diez Dacal, Yin Dong, James E. Dunford, Renzo Guerrini, Adrian L. Harris, Jane Hartley, Georg Hollander, Kassim Javaid, Maureen Kane, Deirdre Kelly, Dominic Kelly, Samantha J. L. Knight, Alexandra Y. Kreins, Erika M. Kvikstad, Craig B. Langman, Tracy Lester, Kate E. Lines, Simon R. Lord, Xin Lu, Sahar Mansour, Adnan Manzur, Reza Maroofian, Brian Marsden, Joanne Mason, Simon J. McGowan, Davide Mei, Hana Mlcochova, Yoshiko Murakami, Andrea H. Németh, Steven Okoli, Elizabeth Ormondroyd, Lilian Bomme Ousager, Jacqueline Palace, Smita Y. Patel, Melissa M. Pentony, Chris Pugh, Aboulfazl Rad, Archana Ramesh, Simone G. Riva, Irene Roberts, Noémi Roy, Outi Salminen, Kyleen D. Schilling, Caroline Scott, Arjune Sen, Conrad Smith, Mark Stevenson, Rajesh V. Thakker, Stephen R. F. Twigg, Holm H. Uhlig, Richard van Wijk, Barbara Vona, Steven Wall, Jing Wang, Hugh Watkins, Jaroslav Zak, Anna H. Schuh, Usha Kini, Andrew O. M. Wilkie, Niko Popitsch, Jenny C. Taylor
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Whole genome sequencing is increasingly being used for the diagnosis of patients with rare diseases. However, the diagnostic yields of many studies, particularly those conducted in a healthcare setting, are often disappointingly l
Externí odkaz:
https://doaj.org/article/c9f00f4d0c70402d8c69f3f7e4981fbc
Autor:
Mandy M. Chan, Sabine Daemen, Joseph W. Beals, Marina Terekhova, Bin Q. Yang, Christina F. Fu, Li He, Arick C. Park, Gordon I. Smith, Babak Razani, Kathleen Byrnes, Wandy L. Beatty, Shaina R. Eckhouse, J. Christopher Eagon, Daniel Ferguson, Brian N. Finck, Samuel Klein, Maxim N. Artyomov, Joel D. Schilling
Publikováno v:
JHEP Reports, Vol 5, Iss 11, Pp 100877- (2023)
Background & Aims: Metabolic dysfunction-associated fatty liver disease (MAFLD) is a common complication of obesity with a hallmark feature of hepatic steatosis. Recent data from animal models of MAFLD have demonstrated substantial changes in macroph
Externí odkaz:
https://doaj.org/article/899e9858356b4c83b39c77d67e35c9a8
Autor:
R. J. Heim, A. Yurtaev, A. Bucharova, W. Heim, V. Kutskir, K.-H. Knorr, C. Lampei, A. Pechkin, D. Schilling, F. Sulkarnaev, N. Hölzel
Publikováno v:
Biogeosciences, Vol 19, Pp 2729-2740 (2022)
Fires are predicted to increase in Arctic regions due to ongoing climate change. Tundra fires can alter carbon and nutrient cycling and release a substantial quantity of greenhouse gases with global consequences. Yet, the long-term effects of tundra
Externí odkaz:
https://doaj.org/article/db352fdd514c4227908078354cf45c60
Autor:
Susheel K. Gunasekar, John Heebink, Danielle H. Carpenter, Ashutosh Kumar, Litao Xie, Haixia Zhang, Joel D. Schilling, Rajan Sah
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
Healthy expansion of adipose tissue is critical for the maintenance of metabolic health, providing an optimized reservoir for energy storage in the form of triacylglycerol-rich lipoproteins. Dysfunctional adipocytes that are unable to efficiently sto
Externí odkaz:
https://doaj.org/article/14ee9bf53bc94ff0b590de2094e4a81a
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100511- (2021)
Summary: Recently, it has become evident that macrophage diversity increases in the liver during the pathogenesis of non-alcoholic steatohepatitis (NASH). Here, we provide a detailed protocol for the analysis of liver macrophage subsets in mice with
Externí odkaz:
https://doaj.org/article/59610ce52da349489541e12129a2fa9e
Autor:
Lindsay M. Henderson, Renee F. Robinson, Lily Ray, Burhan A. Khan, Tianran Li, Denise A. Dillard, Brian D. Schilling, Mike Mosley, Patricia L. Janssen, Alison E. Fohner, Allan E. Rettie, Kenneth E. Thummel, Timothy A. Thornton, David L. Veenstra
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 3, Pp 312-320 (2019)
Alaska Native and American Indian (AN/AI) people have unique pharmacogene variation that may affect warfarin disposition and therapeutic response. We performed targeted genotyping for cytochrome P450 (CYP)2C9, vitamin K epoxide oxidase reductase comp
Externí odkaz:
https://doaj.org/article/24dfd5d4d6b04ffdb379e9c74e4862ad
Publikováno v:
The American Journal of Cardiology. 195:83-90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a9d6539538320278166347f7b77c69c
https://doi.org/10.1016/j.amjcard.2023.02.029
https://doi.org/10.1016/j.amjcard.2023.02.029
Autor:
Jason Liu, MD,, Bin Q. Yang, MD,, Akinobu Itoh, MD, PhD,, Mohammed Faraz Masood, MD,, Justin C. Hartupee, MD, PhD,, Joel D. Schilling, MD, PhD
Publikováno v:
Transplantation Direct, Vol 7, Iss 1, p e642 (2021)
Background. In October 2018, a new heart allocation policy was implemented with intent of prioritizing the sickest patients and decreasing waitlist time. We examined the effects of the new policy on transplant practices and outcomes 1 year before and
Externí odkaz:
https://doaj.org/article/7e9fe018669b4968b985dcc05f031bbb
Autor:
Sabine Daemen, Anastasiia Gainullina, Gowri Kalugotla, Li He, Mandy M. Chan, Joseph W. Beals, Kim H. Liss, Samuel Klein, Ariel E. Feldstein, Brian N. Finck, Maxim N. Artyomov, Joel D. Schilling
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108626- (2021)
Summary: Macrophage-mediated inflammation is critical in the pathogenesis of non-alcoholic steatohepatitis (NASH). Here, we describe that, with high-fat, high-sucrose-diet feeding, mature TIM4pos Kupffer cells (KCs) decrease in number, while monocyte
Externí odkaz:
https://doaj.org/article/2d415d29b48b4ca78ceb4721531288bc
Autor:
Pallavi Chandra, Li He, Matthew Zimmerman, Guozhe Yang, Stefan Köster, Mireille Ouimet, Han Wang, Kathyrn J. Moore, Véronique Dartois, Joel D. Schilling, Jennifer A. Philips
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Macrophage activation involves metabolic reprogramming to support antimicrobial cellular functions. How these metabolic shifts influence the outcome of infection by intracellular pathogens remains incompletely understood. Mycobacterium tuber
Externí odkaz:
https://doaj.org/article/9440bf7fd7254ee79c47ed8d7a264eb2