Zobrazeno 1 - 10
of 341
pro vyhledávání: '"D Saba"'
Autor:
Nancy Keller, Julian Midgley, Ehtesham Khalid, Harry Lesmana, Georgie Mathew, Christine Mincham, Norbert Teig, Zubair Khan, Indu Khosla, Sam Mehr, Tulay Guran, Kathrin Buder, Hong Xu, Khalid Alhasan, Gonul Buyukyilmaz, Nicole Weaver, Julie D. Saba
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Background Sphingosine-1-phosphate lyase insufficiency syndrome (SPLIS) is a recently recognized inborn error of metabolism associated with steroid-resistant nephrotic syndrome as well as adrenal insufficiency and immunological, neurological
Externí odkaz:
https://doaj.org/article/001681b6efb54f18aee01a6b8c1590c9
Autor:
Yadi Tang, Mariola Majewska, Britta Leß, Ilir Mehmeti, Philipp Wollnitzke, Nina Semleit, Bodo Levkau, Julie D. Saba, Gerhild van Echten-Deckert, Ewa Gurgul-Convey
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 8, Pp 100587- (2024)
Lipotoxicity has been considered the main cause of pancreatic beta-cell failure during type 2 diabetes development. Lipid droplets (LD) are believed to regulate the beta-cell sensitivity to free fatty acids (FFA), but the underlying molecular mechani
Externí odkaz:
https://doaj.org/article/f3e16ef9cddd4886b684f4887a91e450
Autor:
Krishan B. Atreya, Julie D. Saba
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
In 2017, an inborn error of metabolism caused by recessive mutations in SGPL1 was discovered. The disease features steroid-resistant nephrotic syndrome, adrenal insufficiency, and neurological defects. The latter can include sensorineural hearing los
Externí odkaz:
https://doaj.org/article/fd1bea855dea4a6b8711d426fee11e76
Publikováno v:
Iranica Journal of Energy and Environment, Vol 12, Iss 2, Pp 155-160 (2021)
An objective analysis of the wind atlas map of the region of Adrar (Algeria) at a height of 10 meters above ground is essential, in order to classify these velocities according to the Pacific Northwest Laboratory (PNL) classification, and then to dev
Externí odkaz:
https://doaj.org/article/dc645121d05045db929f2cd8138d7073
Fifty years of lyase and a moment of truth: sphingosine phosphate lyase from discovery to disease[S]
Autor:
Julie D. Saba
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 3, Pp 456-463 (2019)
Sphingosine phosphate lyase (SPL) is the final enzyme in the sphingolipid degradative pathway, catalyzing the irreversible cleavage of long-chain base phosphates (LCBPs) to yield a long-chain aldehyde and ethanolamine phosphate (EP). SPL guards the s
Externí odkaz:
https://doaj.org/article/5f245d71c25b40f98216ba907893242f
Autor:
Piming Zhao, Gizachew B. Tassew, Joanna Y. Lee, Babak Oskouian, Denise P. Muñoz, Jeffrey B. Hodgin, Gordon L. Watson, Felicia Tang, Jen-Yeu Wang, Jinghui Luo, Yingbao Yang, Sarah King, Ronald M. Krauss, Nancy Keller, Julie D. Saba
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
Sphingosine-1-phosphate lyase insufficiency syndrome (SPLIS) is a rare metabolic disorder caused by inactivating mutations in sphingosine-1-phosphate lyase 1 (SGPL1), which is required for the final step of sphingolipid metabolism. SPLIS features inc
Externí odkaz:
https://doaj.org/article/9c9d0a0bbea44c69ba3c08fe8f691e88
Autor:
Zahra Pournasiri, Abbas Madani, Fatemeh Nazarpack, John A. Sayer, Zahra Chavoshzadeh, Fatemeh Nili, Paulina Tran, Julie D. Saba, Mahnaz Jamee
Publikováno v:
World Journal of Pediatrics. 19:425-437
Sphingosine-1-phosphate lyase insufficiency syndrome (SPLIS) or nephrotic syndrome type-14 is caused by biallelic mutations in SGPL1. Here, we conducted a systematic review to delineate the characteristics of SPLIS patients.A literature search was pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64810c7781c718ad974c00b71eeeebf5
https://doi.org/10.1007/s12519-022-00615-4
https://doi.org/10.1007/s12519-022-00615-4
Autor:
Julie D. Saba, Andrew R. Lee, Robert Bittman, Hoe Sup Byun, Yaqiong Gong, Padmavathi Bandhuvula, Babak Oskouian, Henrik Fyrst
Supplementary Methods, Figures 1-9, Table 1 from Natural Sphingadienes Inhibit Akt-Dependent Signaling and Prevent Intestinal Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330cbbbe5d08204be44d159d77ab5eed
https://doi.org/10.1158/0008-5472.22383575
https://doi.org/10.1158/0008-5472.22383575
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Publikováno v:
Environmental Monitoring and Assessment. 195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15209d24630fa40d713e46a3bf2a88af
https://doi.org/10.1007/s10661-022-10895-y
https://doi.org/10.1007/s10661-022-10895-y