Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D S Torrance"'
Autor:
K M Mohler, D S Torrance, C A Smith, R G Goodwin, K E Stremler, V P Fung, H Madani, M B Widmer
Publikováno v:
The Journal of Immunology. 151:1548-1561
Two forms (monomeric or dimeric) of the extracellular, ligand-binding portion of the human p80 cell-surface receptor for TNF were used to antagonize TNF activity in vitro and in vivo. The dimeric sTNFR:Fc molecule was a more potent inhibitor of TNF t
Publikováno v:
The Journal of Immunology. 149:2496-2505
Experimental autoimmune encephalomyelitis (EAE) serves as an important animal model for understanding the events that lead to immune-mediated inflammation and tissue destruction within the central nervous system. We have utilized a murine adoptive tr
TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation
Autor:
J J, Peschon, D S, Torrance, K L, Stocking, M B, Glaccum, C, Otten, C R, Willis, K, Charrier, P J, Morrissey, C B, Ware, K M, Mohler
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(2)
The pleiotropic activities of the potent proinflammatory cytokine TNF are mediated by two structurally related, but functionally distinct, receptors, p55 and p75, that are coexpressed on most cell types. The majority of biologic responses classically
Autor:
K M, Mohler, D S, Torrance, C A, Smith, R G, Goodwin, K E, Stremler, V P, Fung, H, Madani, M B, Widmer
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(3)
Two forms (monomeric or dimeric) of the extracellular, ligand-binding portion of the human p80 cell-surface receptor for TNF were used to antagonize TNF activity in vitro and in vivo. The dimeric sTNFR:Fc molecule was a more potent inhibitor of TNF t
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 149(7)
Experimental autoimmune encephalomyelitis (EAE) serves as an important animal model for understanding the events that lead to immune-mediated inflammation and tissue destruction within the central nervous system. We have utilized a murine adoptive tr