Zobrazeno 1 - 10
of 41
pro vyhledávání: '"D S Singer"'
Publikováno v:
The Journal of Immunology. 154:4830-4835
Experimental systemic lupus erythematosus (SLE) can be induced in mice by immunization with a human monoclonal anti-DNA Ab, bearing a major Id 16/6Id. Immunized mice initially produce Abs to 16/6Id, DNA and nuclear Ags, and subsequently develop vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11388f46290dafabe09703f016d8ae88
https://doi.org/10.4049/jimmunol.154.9.4830
https://doi.org/10.4049/jimmunol.154.9.4830
Publikováno v:
The Journal of Immunology. 153:873-880
Experimental SLE can be induced in mice by immunization with a human mAb to DNA (16/6Id). Immunized mice develop Abs to the 16/6Id immunogen, DNA, and nuclear Ags. Subsequently, clinical manifestations of disease develop, including leukopenia, protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::115edd9d8a8ef690782c17780810d0e6
https://doi.org/10.4049/jimmunol.153.2.873
https://doi.org/10.4049/jimmunol.153.2.873
Autor:
J D Weissman, D S Singer
Publikováno v:
Molecular and Cellular Biology. 11:4217-4227
A novel regulatory element which contributes to the regulation of quantitative, tissue-specific differences in gene expression has been found between -771 and -676 bp upstream of the major histocompatibility complex (MHC) class I gene, PD1. Molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e325455626245348eb303579edb575ad
https://doi.org/10.1128/mcb.11.8.4217
https://doi.org/10.1128/mcb.11.8.4217
Autor:
J D Weissman, D S Singer
Publikováno v:
Molecular and Cellular Biology. 11:4228-4234
Expression of a mammalian major histocompatibility complex (MHC) class I gene is in part regulated by a silencer DNA sequence element which binds a complex of silencer factors. This negative regulatory system is shown to be strikingly similar to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f479581b2dfc1abef314ce4bdadf3f1
https://doi.org/10.1128/mcb.11.8.4228-4234.1991
https://doi.org/10.1128/mcb.11.8.4228-4234.1991
Autor:
J D, Weissman, D S, Singer
Publikováno v:
Molecular and Cellular Biology. 11:4217-4227
A novel regulatory element which contributes to the regulation of quantitative, tissue-specific differences in gene expression has been found between -771 and -676 bp upstream of the major histocompatibility complex (MHC) class I gene, PD1. Molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46577c5fcf95593d1d89b940bdd56fdd
https://doi.org/10.1128/mcb.11.8.4217-4227.1991
https://doi.org/10.1128/mcb.11.8.4217-4227.1991
Publikováno v:
Lupus. 14(4)
(NZBxNZW)F1 mice spontaneously develop with age an autoimmune disease that resembles the human disease, systemic lupus erythematosus (SLE). Previous studies have demonstrated that susceptibility to experimentally induced SLE depended on the expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf476fadf40c11f528fc8fa08360ca5
https://pubmed.ncbi.nlm.nih.gov/15864917
https://pubmed.ncbi.nlm.nih.gov/15864917
Autor:
C, Giuliani, G, Napolitano, A, Mastino, S, Di Vincenzo, C, D'Agostini, S, Grelli, I, Bucci, D S, Singer, L D, Kohn, F, Monaco, E, Garaci, C, Favalli
Publikováno v:
European journal of immunology. 30(3)
In this study we examined the effect of the synthetic peptide thymosin-alpha1 (T(alpha)1) on MHC class I expression in FRTL-5 cells. Treatment with T(alpha)1 increased expression of MHC class I surface molecules and mRNA, which reached its peak (153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7958a7caa154a39468a8be5274089edf
https://pubmed.ncbi.nlm.nih.gov/10741392
https://pubmed.ncbi.nlm.nih.gov/10741392
Publikováno v:
European journal of immunology. 29(7)
Mice deficient in beta2-microglobulin expression are resistant to the induction of experimental systemic lupus erythematosus (SLE). The present studies were designed to identify the beta2-microglobulin-dependent cell surface molecule(s) that confers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75883a7e9603b1115eb5a66b9baff720
https://pubmed.ncbi.nlm.nih.gov/10427989
https://pubmed.ncbi.nlm.nih.gov/10427989
Autor:
J R, Rodgers, J M, Levitt, P, Cresswell, K F, Lindahl, D, Mathis, J T, Monaco, D S, Singer, H L, Ploegh, P W, Bryant
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::660018f8ed3a5864a92a639cbf68d1a6
https://pubmed.ncbi.nlm.nih.gov/10375304
https://pubmed.ncbi.nlm.nih.gov/10375304
Publikováno v:
Journal of clinical immunology. 18(2)
(NZB x NZW)F1 mice spontaneously develop with age an autoimmune disease that resembles the human disease, systemic lupus erythematosus (SLE). The present study demonstrates that methimazole (MMI), an agent used in the treatment of autoimmune thyroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba0eb14bc827ed1bc063f8b7f4271c6b
https://pubmed.ncbi.nlm.nih.gov/9533654
https://pubmed.ncbi.nlm.nih.gov/9533654