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of 3
pro vyhledávání: '"D S Compton"'
Publikováno v:
British journal of pharmacology. 134(2)
1. Ezetimibe potently inhibits the transport of cholesterol across the intestinal wall, thereby reducing plasma cholesterol in preclinical animal models of hypercholesterolemia. The effect of ezetimibe on known absorptive processes was determined in
Autor:
M, Van Heek, C F, France, D S, Compton, R L, McLeod, N P, Yumibe, K B, Alton, E J, Sybertz, H R, Davis
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(1)
SCH48461 is a selective and highly potent inhibitor of cholesterol absorption. In rats, SCH48461 is rapidly and completely metabolized in the first pass through the body. To compare the activity of the metabolites of SCH48461 with SCH48461 itself, an
Autor:
M Van Heek, D S Compton, C F France, R P Tedesco, A B Fawzi, M P Graziano, E J Sybertz, C D Strader, H R Davis
Publikováno v:
The Journal of clinical investigation. 99(3)
Leptin administration reduces obesity in leptin-deficient ob/ob mice; its effects in obese humans, who have high circulating leptin levels, remain to be determined. This longitudinal study was designed to determine whether diet-induced obesity in mic