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pro vyhledávání: '"D S, Sachan"'
In a randomised, double-blind placebo-controlled trial, the effects of the administration of oral L-carnitine (2 g/day) for 28 days were compared in the management of 51 (carnitine group) and 50 (placebo group) patients with suspected acute myocardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a11db55bd75f5748de6c833bfc12eb5
https://europepmc.org/articles/PMC2398308/
https://europepmc.org/articles/PMC2398308/
Publikováno v:
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 12(4)
Male Sprague Dawley rats were fed a semisynthetic diet ad libitum, 55% of ad libitum (45% restriction), or supplemented with 1% L-carnitine for 68 days. The LD50 dose of CCl4 was orally administered, and mortality and hepatic lipids were determined.
Autor:
D S, Sachan, W L, Dodson
Publikováno v:
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 11(3)
Effects of 0.5% L-carnitine-supplemented diet on carbon tetrachloride-induced alterations of hepatic and serum lipids were examined in male rats. Treatment with carbon tetrachloride significantly increased hepatic total lipids, triglycerides, and tot
Autor:
N Hongu, D S. Sachan
Publikováno v:
Medicine & Science in Sports & Exercise. 34:S86
Autor:
W L Dodson, D S Sachan
Publikováno v:
Journal of the American College of Nutrition. 6:145-150
Carnitine is necessary for the translocation of fatty acids into the mitochondria, and the relative concentration of carnitine and acylcarnitine in the serum are known to reflect metabolic states. A survey of serum carnitine concentrations was made i
Autor:
D S Sachan, C L Hoppel
Publikováno v:
Biochemical Journal. 188:529-534
Rat kidney homogenates metabolize N6-trimethyl-lysine to N-trimethylammoniobutyrate, but not to carnitine. The first step in this conversion is the hydroxylation of trimethyl-lysine to form 3-hydroxy-N6-trimethyl-lysine. An assay system was developed
Publikováno v:
Drug-nutrient interactions. 5(2)
Interactive combinations of altered zinc and thyroid states were studied in rats to assess pathophysiologic effects. Clinical signs of zinc deficiency or thyroid alteration were limited to effects on growth rate. Changes in organ and glandular weight
Autor:
C. L. Davis, D. S. Sachan
Publikováno v:
Journal of bacteriology. 98(1)
Borrelia sp. B 2 5, when grown in a medium containing [1- 14 C] linoleic acid in an atmosphere of CO 2 , was found to hydrogenate linoleic acid to trans -11-octadecenoic acid.