Zobrazeno 1 - 10
of 37
pro vyhledávání: '"D S, Prough"'
Publikováno v:
Journal of Burn Care & Research. 39:S132-S132
Autor:
C J, Frederickson, L J, Giblin, A, Krezel, D J, McAdoo, R N, Mueller, R N, Muelle, Y, Zeng, R V, Balaji, R, Masalha, R B, Thompson, C A, Fierke, J M, Sarvey, M, de Valdenebro, D S, Prough, M H, Zornow
Publikováno v:
Experimental Neurology. 198:285-293
"Free Zn2+" (rapidly exchangeable Zn2+) is stored along with glutamate in the presynaptic terminals of specific specialized (gluzinergic) cerebrocortical neurons. This synaptically releasable Zn2+ has been recognized as a potent modulator of glutamat
Publikováno v:
Clinical science (London, England : 1979). 101(2)
Autor:
M H, Zornow, D S, Prough
Publikováno v:
New horizons (Baltimore, Md.). 4(1)
Increases in intraneuronal Ca2+ concentration, which accompany cerebral ischemia and traumatic brain injury, initiate a cascade of biochemical events that can eventually result in cell lysis and death. Calcium-channel blockers, in certain experimenta
Autor:
M H, Zornow, D S, Prough
Publikováno v:
New horizons (Baltimore, Md.). 3(3)
Movement of water between the brain and the intravascular space is dependent on osmotic gradients, which may be established by the acute administration of either hyper- or hypo-osmolar solutions. Mannitol, a hypertonic crystalloid solution, is common
Publikováno v:
New horizons (Baltimore, Md.). 3(3)
Both experimental traumatic brain injury and clinical traumatic brain injury appear to render the brain more vulnerable to a second ischemic insult. The mechanisms of enhanced vulnerability to subsequent ischemia appear to include a reduced ability t
Autor:
W E, Johnston, D A, Stump, D S, DeWitt, J, Vinten-Johansen, W K, O'Steen, R L, James, D S, Prough
Publikováno v:
Circulation. 88(5 Pt 2)
Gaseous microemboli during cardiac surgery may damage the brain by reducing cerebral blood flow (CBF). We examined whether the incidence of gaseous microemboli during 150-minute hypothermic (28 degrees C) cardiopulmonary bypass (CPB) adversely affect
Autor:
A T, Rogers, D S, Prough, R C, Roy, G P, Gravlee, D A, Stump, A R, Cordell, J, Phipps, C L, Taylor
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 103(2)
Recent experimental and clinical investigations provide conflicting evidence regarding the effects of changes in the systemic flow rate from the pump oxygenator on cerebral blood flow and the cerebral metabolic rate of oxygen consumption. However, th
Publikováno v:
Surgery. 110(3)
We addressed the impact on intracranial pressure (ICP) of posthemorrhage fluid resuscitation with a protocol in which additional fluid was infused to maintain a stable cardiac output after an initial bolus of fluid was infused. Anesthetized, mechanic
Autor:
S A, Mills, D S, Prough
Publikováno v:
Seminars in thoracic and cardiovascular surgery. 3(1)
Few patients are neurologically devastated following cardiac surgery. However, a substantial number of patients suffer sufficient deterioration in neurologic and neuropsychologic function that the quality of their recovery is limited. Intensive resea