Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium.

Autor: J M Vonk, S Scholtens, D S Postma, M F Moffatt, D Jarvis, A Ramasamy, M Wjst, E R Omenaas, E Bouzigon, F Demenais, R Nadif, V Siroux, A V Polonikov, M Solodilova, V P Ivanov, I Curjuric, M Imboden, A Kumar, N Probst-Hensch, L M Ogorodova, V P Puzyrev, E Yu Bragina, M B Freidin, I M Nolte, A M Farrall, W O C M Cookson, D P Strachan, G H Koppelman, H M Boezen

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0172716 (2017)

BACKGROUND:Genome-wide association studies have identified novel genetic associations for asthma, but without taking into account the role of active tobacco smoking. This study aimed to identify novel genes that interact with ever active tobacco smok

Externí odkaz: https://doaj.org/article/496346024af446f4a8ef3bcdbd0b4d4b

Cell surface antigen expression by peripheral blood monocytes in allergic asthma: results of 2.5 years therapy with inhaled beclomethasone dipropionate

Autor: W. A. T. Slieker, P. Th. W. van Hal, J. M. Wijkhuijs, J. P. M. Hopstaken-Broos, J. A. Noordhoek, S. E. Overbeek, P. G. H. Mulder, D. S. Postma, H. C. Hoogsteden

Publikováno v: Mediators of Inflammation, Vol 5, Iss 5, Pp 362-369 (1996)

At present, inhaled glucocorticoids are widely accepted as the therapy of choice in chronic asthma. Treatment with inhaled glucocorticoids significantly suppresses local airway inflammation in asthmatics, but may also have systemic effects, e.g. a re

Externí odkaz: https://doaj.org/article/a8b14983bf604f49bb18240582c89143

Successful Smoking Cessation in COPD: Association with Comorbidities and Mortality

Autor: H. Kupiainen, V. L. Kinnula, A. Lindqvist, D. S. Postma, H. M. Boezen, T. Laitinen, M. Kilpeläinen

Publikováno v: Pulmonary Medicine, Vol 2012 (2012)

Smoking cessation is the cornerstone of COPD management, but difficult to achieve in clinical practice. The effect of comorbidities on smoking cessation and risk factors for mortality were studied in a cohort of 739 COPD patients recruited in two Fin

Externí odkaz: https://doaj.org/article/5c7f41ac158143aa9c8f03317fc31803

TSANZ Poster Presentations

Autor: Barry J. Make, Javier Nuevo, Niklas Karlsson, Alvar Agusti, J Vestbo, X Wang, Richard Beasley, Lance Brannman, Christina Keen, E.H.D. Bel, Fredrik Nyberg, M G De Verdier, Christer Janson, Asparuh Gardev, A Sveréus, Richard J. Martin, Stephen I. Rennard, D. S. Postma, Helen K. Reddel, J Hiller, Aruna T. Bansal, Ian D. Pavord, David Price, D Wong, Simon Young

Publikováno v: Respirology. 22:101-193

Suitability of australian electronic medical records to guide the design of the novelty study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a4517706987c8af9165c93abc18e2d
https://doi.org/10.1111/resp.13010

A genome-wide association meta-analysis identifies new childhood obesity loci

Autor: Craig E. Pennell, Chris Power, Johannes Hebebrand, David Meyre, Jean Dallongeville, Pma Sleiman, Mark I. McCarthy, Joel N. Hirschhorn, Nicholas J. Timpson, Nicole M. Warrington, Rjp van der Valk, Karani Santhanakrishnan Vimaleswaran, A Pouta, Mònica Guxens, Mariona Bustamante, Luis A. Moreno, M-R Jarvelin, Fredrick R. Schumacher, Aline Meirhaeghe, Charlotte E. Neville, Beatriz Valcarcel, Eleanor Wheeler, Hakon Hakonarson, Stephen O'Rahilly, D. S. Postma, Albert Hofman, Fernando Rivadeneira, Johan G. Eriksson, Hans Bisgaard, George McMahon, Vwv Jaddoe, I. S. Farooqi, Shikta Das, Diane J. Berry, Eskil Kreiner-Møller, Mohamed T. Hassanein, J. C. de Jongste, Joachim Heinrich, Olli T. Raitakari, Jessica L. Buxton, Aarno Palotie, W. J. Gauderman, Paul Elliott, C. Lecoeur, Reedik Mägi, Elina Hyppönen, C M van Duijn, B. St Pourcain, Frank D. Gilliland, Susan M. Ring, John P. Kemp, Rany M. Salem, Lyle J. Palmer, Terho Lehtimäki, Philippe Froguel, Ivonne Jarick, Cag Boreham, Elisabeth Thiering, Dorret I. Boomsma, Sfa Grant, A.-L. Hartikainen, André Scherag, Panagiotis Deloukas, Claus Holst, Jianhua Zhao, André G. Uitterlinden, Robert I. Berkowitz, Cecilia M. Lindgren, Tia Sorensen, Aif Blakemore, Mingyao Li, George Davey Smith, Dennis O. Mook-Kanamori, H R Taal, David M. Evans, Diana L. Cousminer, Matthew W. Gillman, Jonathan P. Bradfield, E. Widen, Anke Hinney, Inês Barroso

Publikováno v: Nature Genetics, 44(5), 526-531e1. Nature Publishing Group
Nature genetics, vol 44, iss 5
Nature Genetics, 44(5), 526-+. Nature Publishing Group
Nature Genetics; Vol 44
Nature genetics
Nature Genetics, 44(5), 526-532. Nature Publishing Group
Ожирение и метаболизм, Vol 9, Iss 1 (2012)
Bradfield, J P, Taal, H R, Timpson, N J, Scherag, A, Lecoeur, C, Warrington, N M, Hypponen, E, Holst, C, Valcarcel, B, Thiering, E, Salem, R M, Schumacher, F R, Cousminer, D L, Sleiman, P M A, Zhao, J, Berkowitz, R I, Vimaleswaran, K S, Jarick, I, Pennell, C E, Evans, D M, St Pourcain, B, Berry, D J, Mook-Kanamori, D O, Hofman, A, Rivadeneira, F, Uitterlinden, A G, van Duijn, C M, van der Valk, R J P, de Jongste, J C, Postma, D S, Boomsma, D I, Gauderman, W J, Hassanein, M T, Lindgren, C M, Mägi, R, Boreham, C A G, Neville, C E, Moreno, L A, Elliott, P, Pouta, A, Hartikainen, A-L, Li, M, Raitakari, O, Lehtimäki, T, Eriksson, J G, Palotie, A, Dallongeville, J, Das, S, Deloukas, P, McMahon, G, Ring, S M, Kemp, J P, Buxton, J L, Blakemore, A I F, Bustamante, M, Guxens, M, Hirschhorn, J N, Gillman, M W, Kreiner-Møller, E, Bisgaard, H, Gilliland, F D, Heinrich, J, Wheeler, E, Barroso, I, O'Rahilly, S, Meirhaeghe, A, Sørensen, T I A, Power, C, Palmer, L J, Hinney, A, Widen, E, Farooqi, I S, McCarthy, M I, Froguel, P, Meyre, D, Hebebrand, J, Järvelin, M J, Jaddoe, V W V, Smith, G D, Hakonarson, H & Grant, S F A 2012, ' A genome-wide association meta-analysis identifies new childhood obesity loci ', Nature Genetics, vol. 44, no. 5, pp. 526-532 . https://doi.org/10.1038/ng.2247
Nature Genetics

Multiple genetic variants have been associated with adult obesity and a few with severe obesity in childhood; however, less progress has been made in establishing genetic influences on common early-onset obesity. We performed a North American, Austra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f880f61d6afe73241feeb22a7a0f214a
https://ora.ox.ac.uk/objects/uuid:96f4bbd6-9965-4488-bd10-c99d0e45ba6b