Výsledky vyhledávání - "D S, Mikhaĭlenko"

[Markers for non-invasive molecular genetic diagnosis of oncourological diseases]

Autor: D S, Mikhaĭlenko, D V, Perepechin, O I, Apolikhin, G D, Efremov, A V, Sivkov

Publikováno v: Urologiia (Moscow, Russia : 1999). (5)

Currently, there is accumulated mass of data on the molecular-genetic disorders in prostate cancer (PCa), bladder cancer (BC) and renal cancer (RC). Tumor cells in these diseases are present in the urine sediment; their number is sufficient for molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ef9e59f51e3d936ef04a5d4e7067a0e
https://pubmed.ncbi.nlm.nih.gov/25807773

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[Structural and functional analysis of tumor genomes and the development of test systems for early diagnosis, prognosis and cancer therapy optimization]

Autor: D V, Zaletaev, V V, Strel'nikov, M V, Nemtsova, O V, Babenko, E B, Kuznetsova, V V, Zemliakova, T V, Kekeeva, D S, Mikhaĭlenko, A S, Tanas, V V, Rudenko, A Iu, Babaian, E A, Alekseeva, O A, Simonova

Publikováno v: Vestnik Rossiiskoi akademii meditsinskikh nauk. (9)

The article discusses results of the structural and functional analysis of molecular genetic abnormalities in various malignant tumors. Investigations have discovered more than 20 new markers for sporadic breast cancer. Several of them formed the tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2ef66454df3bf0205bb28578ac0dd5b5
https://pubmed.ncbi.nlm.nih.gov/24624866

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[Allelic disbalance in 1q32 area and microsatellite instability renal papillary adenocarcinoma]

Autor: L V, Moskvinina, D S, Mikhaĭlenko, Iu Iu, Andreeva, V V, Strel'nikov, D V, Zaletaev

Publikováno v: Arkhiv patologii. 74(2)

Papillary adenocarcinoma is an abundant form of renal cell carcinoma. At present any diagnostic and prognostic molecular markers of papillary adenocarcinoma are absent, however some cytogenetic and molecular-genetic features of disease are known. Acc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::04feddc811d851931525a749e56b1cf6
https://pubmed.ncbi.nlm.nih.gov/22880406

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[Localization of point mutations in the coding part of the VHL gene in clear cell renal cancer]

Autor: D S, Mikhaĭlenko, M V, Grigor'eva, I G, Rusakov, R V, Kurynin, A M, Popov, M V, Peters, V B, Matveev, E S, Iakovlev, D A, Nosov, L N, Liubchenko, S A, Tiuliandin, V V, Strel'nikov, D V, Zaletaev

Publikováno v: Molekuliarnaia biologiia. 46(1)

VHL gene is often inactivated in sporadic clear cell renal cancer (CCRC) due to somatic mutations, and it's germline mutations cause hereditary CCRC--von Hippel-Lindau syndrome. Localization of mutations in VHL, identification of new mutations and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5bbc76fa60759392dd6c5e2b757a44e1
https://pubmed.ncbi.nlm.nih.gov/22642103

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[Molecular-genetic analysis of clonal intratumoral heterogeneity on colorectal adenocarcinomas]

Autor: M N, Nemtsova, E M, Pal'tseva, A Iu, Babaian, D S, Mikhaĭlenko, O V, Babenko, O Iu, Samofalova, P V, Tsar'kov, D V, Zaletaev

Publikováno v: Molekuliarnaia biologiia. 42(6)

We have examined the existence of intratumoral genetic heterogeneity for LOH on chromosomes 9p21 (p16, p15, p19), 13p14 (RB1), 10q23 (PTEN), 17p (TP53), microsatellite instability and K-RAS point mutations on four different segments of sporadic color

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1170b4f708a0a198d025a710920a9017
https://pubmed.ncbi.nlm.nih.gov/19140325

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[Inactivation of the VHL gene in sporadic clear cell renal cancer]

Autor: D S, Mikhaĭlenko, R B, Kurynin, A M, Popov, O B, Kariakin, M E, Enikeev, Iu G, Aliaev, M V, Nemtsova, D V, Zaletaev

Publikováno v: Molekuliarnaia biologiia. 42(1)

Renal cell carcinoma is the most common variant of the kidney cancer, which accounts approximately 75% patients with this disease. The majority of those tumors are characterized by inactivation of the VHL gene suppressor as a result of mutations, all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5737db34903e479d417fd025b1a588b6
https://pubmed.ncbi.nlm.nih.gov/18389622

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[Analysis of polymorphic variants of gene GIPC1 CGG repeats in healthy individuals and in patients with breast cancer and non-small cell lung cancer]

Autor: D S, Mikhaĭlenko, L N, Liubchenko, I B, Zborovskaia, V V, Strel'nikov, D V, Zaletaev

Publikováno v: Genetika. 41(9)

The GIPC1 gene product promotes clustering of some transmembrane receptors, including those involved in carcinogenesis, and protects them against ubiquitin-dependent degradation. The 5' untranslated region of GIPC1 contains a polymorphic trinucleotid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e1112be4cbf7a00769cfd498f008ca8
https://pubmed.ncbi.nlm.nih.gov/16240642

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