Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D S, Leibowitz"'
Publikováno v:
Journal of Biological Chemistry. 269:10820-10829
A reciprocal translocation between chromosomes 9 and 22 creates the Philadelphia (Ph1) chromosome in chronic myelogenous leukemia. This translocation results in the fusion of the ABL and the BCR genes to form a BCR/ABL fusion gene, the product of whi
Publikováno v:
The Journal of Experimental Medicine
Enforced expression of p210bcr-abl transforms interleukin 3 (IL-3)-dependent hematopoietic cell lines to growth factor-independent proliferation. It has been demonstrated that nonreceptor tyrosine kinase oncogenes may couple to the p21ras pathway to
Autor:
Burgess Gs, Boswell Hs, Keisuke Miyazawa, Kamran Gharehbaghi, D. S. Leibowitz, R. A. Mandanas, T Tauchi, Hiremagalur N. Jayaram
Publikováno v:
Blood. 82:1838-1847
The p21 RAS product has been implicated as part of the downstream signaling of certain nonreceptor tyrosine kinase oncogenes and several growth factor receptor-ligand interactions. We have reported that the chronic myelogenous leukemia oncogene p210
Publikováno v:
Leukemia. 9(9)
Experiments were performed to elucidate the mechanism through which p210 BCR-ABL, by its downstream signals, regulates c-myc messenger RNA expression in hematopoietic cells. We studied a model system in which stable expression of p210 BCR-ABL in inte
Publikováno v:
The Journal of biological chemistry. 269(14)
A reciprocal translocation between chromosomes 9 and 22 creates the Philadelphia (Ph1) chromosome in chronic myelogenous leukemia. This translocation results in the fusion of the ABL and the BCR genes to form a BCR/ABL fusion gene, the product of whi