Zobrazeno 1 - 10
of 13
pro vyhledávání: '"D S, Leake"'
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 12, Pp 2504-2512 (1995)
Oxidized low density lipoprotein (LDL) may play a significant role in atherosclerosis. We have investigated the effect of pH on the oxidation of LDL by iron or copper. When LDL was oxidized by iron in the presence of cysteine in either Hanks' balance
Externí odkaz:
https://doaj.org/article/779e33d1d2b44499b14fc67701251724
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 12, Pp 2504-2512 (1995)
Oxidized low density lipoprotein (LDL) may play a significant role in atherosclerosis. We have investigated the effect of pH on the oxidation of LDL by iron or copper. When LDL was oxidized by iron in the presence of cysteine in either Hanks' balance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376101d4bef1f0c328c2751314280ac0
http://www.sciencedirect.com/science/article/pii/S0022227520410879
http://www.sciencedirect.com/science/article/pii/S0022227520410879
Autor:
D S Leake
Publikováno v:
Heart. 69:476-478
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cfe97116aac6013cc78bea85d14a20
https://doi.org/10.1136/hrt.69.6.476
https://doi.org/10.1136/hrt.69.6.476
Autor:
C H, MacPhee, K E, Moores, H F, Boyd, D, Dhanak, R J, Ife, C A, Leach, D S, Leake, K J, Milliner, R A, Patterson, K E, Suckling, D G, Tew, D M, Hickey
Publikováno v:
The Biochemical journal. 338
A novel and potent azetidinone inhibitor of the lipoprotein-associated phospholipase A2 (Lp-PLA2), i.e. platelet-activating factor acetylhydrolase, is described for the first time. This inhibitor, SB-222657 (Ki=40+/-3 nM, kobs/[I]=6. 6x10(5) M-1.s-1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::626460f359a74e1b15f305f443280f4d
https://pubmed.ncbi.nlm.nih.gov/10024526
https://pubmed.ncbi.nlm.nih.gov/10024526
Autor:
D S, Leake
Publikováno v:
Lancet (London, England). 347(9016)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b342bb184c1f8647406ace5bf784705
https://pubmed.ncbi.nlm.nih.gov/8642974
https://pubmed.ncbi.nlm.nih.gov/8642974
Publikováno v:
Advances in experimental medicine and biology. 264
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3134153752ce613aa21895943073a53f
https://pubmed.ncbi.nlm.nih.gov/2173869
https://pubmed.ncbi.nlm.nih.gov/2173869
Autor:
S M, Rankin, D S, Leake
Publikováno v:
Agents and actions. Supplements. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5fa6b21f6e3cc916a32847cb4123407
https://pubmed.ncbi.nlm.nih.gov/3064571
https://pubmed.ncbi.nlm.nih.gov/3064571
Autor:
D S, Leake, T J, Peters
Publikováno v:
Biochimica et biophysica acta. 664(1)
Low density lipoproteins have been implicated in the pathogenesis of atherosclerosis. A study has therefore been made of their proteolytic degradation by homogenates of cultured smooth muscle cells from the pig aorta. The pH optimum of proteolysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0726d773969829d5e39699eb0b5de26b
https://pubmed.ncbi.nlm.nih.gov/7016193
https://pubmed.ncbi.nlm.nih.gov/7016193
Autor:
D S, Leake, D E, Bowyer
Publikováno v:
Progress in biochemical pharmacology. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cbb8ea92664c846c4d99a5e04ae04808
https://pubmed.ncbi.nlm.nih.gov/563075
https://pubmed.ncbi.nlm.nih.gov/563075
Publikováno v:
Thrombosis and haemostasis. 47(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8a2a9cf2a97c65a338b95978167d2bf
https://pubmed.ncbi.nlm.nih.gov/6287662
https://pubmed.ncbi.nlm.nih.gov/6287662