Zobrazeno 1 - 10
of 58
pro vyhledávání: '"D S, Khodyrev"'
Autor:
T. M. Zavarykina, P. K. Lomskova, M. A. Kapralova, O. O. Gordeeva, I. P. Ganshina, D. S. Khodyrev, S. V. Khokhlova, I. V. Kolyadina
Publikováno v:
Опухоли женской репродуктивной системы, Vol 18, Iss 4, Pp 69-80 (2023)
Background. Breast cancer is the most common cancer among women. Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, in which there are no special targets for therapy. Therefore chemotherapy is still leading treatmen
Externí odkaz:
https://doaj.org/article/5ed10ee33c6541e192682c3fd761a34a
Publikováno v:
Клиническая практика, Vol 11, Iss 1, Pp 21-29 (2020)
Background. The development of hereditary cancer syndromes is caused by genetic disorders in the DNA repair system, which consists of more than 100 genes. However, at present, in the majority of medical centers in Russia, the diagnosis of hereditary
Externí odkaz:
https://doaj.org/article/1db3ad98139846e7bd0a2c37c72e31ed
Autor:
O I Brovkina, M G Gordiev, A N Toropovskiy, D S Khodyrev, Au Vyacheslavovich Nikitin, A V Averyanov
Publikováno v:
Клиническая практика, Vol 8, Iss 4, Pp 8-14 (2017)
The “gold standard” of diagnosis of colorectal cancer (CRC) is a colonoscopy. Despite the high reliability, this method is not applicable in large-scale population screening or in estimation of the disease dynamics in a particular patient. In thi
Externí odkaz:
https://doaj.org/article/6287af506bec4c64ae43c52452be2d9d
Autor:
O. I. Brovkina, M. G. Gordiev, R. F. Enikeev, M. O. Druzhkov, L. Kh. Shigapova, E. I. Shagimardanova, O. А. Gusev, V. V. Kosiy, D. S. Khodyrev, A. G. Kedrova, R. Sh. Khasanov, A. G. Nikitin
Publikováno v:
Опухоли женской репродуктивной системы, Vol 13, Iss 2, Pp 61-67 (2017)
Introduction. Development of hereditary ovarian cancer (OC) and breast cancer (BC) is caused by genetic abnormalities in the DNA reparation system consisting of more than 100 genes. However, currently in the majority of medical centers in Russia, dia
Externí odkaz:
https://doaj.org/article/d351bc03447e4ae2a36b096e9306e9f1
Autor:
P. K. Brenner, M. A. Kapralova, D. S. Khodyrev, S. V. Khokhlova, G. N. Khabas, A. V. Asaturova, Yu. V. Nosova, L. N. Kayumova, T. M. Zavarykina
Publikováno v:
Russian Journal of Genetics. 58:1154-1158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac837449adb37110aad6dc3ae85ec465
https://doi.org/10.1134/s102279542209006x
https://doi.org/10.1134/s102279542209006x
Publikováno v:
Клиническая практика, Vol 7, Iss 4, Pp 15-20 (2016)
Definition of epigenetic disorders is important for early diagnosis of colorectal cancer. To obtain a model of diagnostic test system with high sensitivity and specificity, we determined the frequency of methylation in SEPT9 and VIM genes. Epigenetic
Externí odkaz:
https://doaj.org/article/ce440d052d7b42bb9da044368d740241
Autor:
D S Khodyrev, N S Kulagina, O I Brovkina, V E Pokrovsky, M G Gordiev, A S Кelekhsaeva, A G Nikitin, A V Averyanov
Publikováno v:
Клиническая практика, Vol 7, Iss 4, Pp 27-33 (2016)
In the 21st century is an acute problem to find effective and inexpensive methods for the early detection of lung cancer. Patients suspected of having a malignant disease of the lungs, generally undergo clinical studies such as CT scans of the chest
Externí odkaz:
https://doaj.org/article/2b0e8ea88b224c2d90c15b448b5bc28f
Autor:
Eleonora A. Braga, S S Lukina, D. S. Khodyrev, A. M. Burdennyy, A. V. Karpukhin, Vitaly I. Loginov, I. V. Pronina, E. A. Filippova, Tatiana P. Kazubskaya
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:67-71
Systemic analysis of the relationship between the levels of methylation of 21 microRNA genes and the parameters of breast cancer progression was performed on a representative sample of 91 paired specimens of breast cancer and histologically normal ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b177a9bb20f9d691f1ac875c6c5f846
https://doi.org/10.1007/s10517-021-05333-x
https://doi.org/10.1007/s10517-021-05333-x
Autor:
Eleonora A. Braga, A. M. Burdennyy, S S Lukina, I. V. Pronina, Vitaly I. Loginov, Tatiana P. Kazubskaya, N A Ivanova, D. S. Khodyrev, E. A. Filippova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:57-62
Changes in the methylation levels of 21 microRNA genes in 91 breast cancer samples in comparison with paired samples of histologically unchanged tissue were studied by quantitative methylation-specific PCR. For 19 microRNA genes, a significant increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3502e9c629fab3bec5f7ba78243f6254
https://doi.org/10.1007/s10517-021-05331-z
https://doi.org/10.1007/s10517-021-05331-z
Autor:
T. P. Kazubskaya, V. I. Loginov, D. S. Khodyrev, V. D. Ermilova, Yu. G. Payanidi, N. V. Chkhikvadze, V. Yu. Selchuk, E. A. Braga
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 1, Pp 61-68 (2014)
The methylation status of the tumor suppressor genes RASSF1A, RARβ2, and SEMA3B was studied in the samples of cancer and its histologically normal tissue of the breast and ovaries. The high rate of abnormal methylation of the CpG islet in the RASSF1
Externí odkaz:
https://doaj.org/article/43eb52fcc502467487c6a012e9234ce8