Zobrazeno 1 - 10
of 16
pro vyhledávání: '"D S, Greene"'
Publikováno v:
Journal of clinical pharmacology. 40(12 Pt 2)
Two randomized crossover studies were conducted to evaluate the pharmacokinetics (including food effect) of fixed-combination metformin/glyburide tablets. Pharmacokinetics and bioavailability of two strengths (500 mg/2.5 mg and 500 mg/5 mg) of metfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c85bab22b0d70e95bdf1b1088ee43d54
https://pubmed.ncbi.nlm.nih.gov/11185672
https://pubmed.ncbi.nlm.nih.gov/11185672
Publikováno v:
British journal of clinical pharmacology. 50(4)
The purpose of this in vivo human study was to assess the effect of altered gastric emptying and gastrointestinal motility on the absorption of metformin in healthy subjects.An open-label, three treatment, three period crossover study was conducted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7c05ce530152d9866930ef4850ee566
https://pubmed.ncbi.nlm.nih.gov/11012555
https://pubmed.ncbi.nlm.nih.gov/11012555
Autor:
R C, Dockens, K S, Santone, J G, Mitroka, R A, Morrison, M, Jemal, D S, Greene, R H, Barbhaiya
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 28(8)
Ifetroban is a potent and selective thromboxane receptor antagonist. This study was conducted to characterize the pharmacokinetics, absolute bioavailability, and disposition of ifetroban after i.v. and oral administrations of [14C]ifetroban or [3H]if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0d534f76411cb890f40d13ab9636067
https://pubmed.ncbi.nlm.nih.gov/10901709
https://pubmed.ncbi.nlm.nih.gov/10901709
Publikováno v:
Biopharmaceuticsdrug disposition. 19(6)
Bioavailability of avitriptan was found to decrease significantly when administered 5 min after a standard high fat meal. The studies described herein were carried out to gain insight into the mechanism of this food effect. A series of studies were c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcebcbc3d91f8e8d5db6d59549e1e50b
https://pubmed.ncbi.nlm.nih.gov/9737819
https://pubmed.ncbi.nlm.nih.gov/9737819
Publikováno v:
Biopharmaceuticsdrug disposition. 19(3)
The objectives of this study were to assess the effect of food and gender on the pharmacokinetics of avitripan. A group of 12 healthy men and 12 healthy women was administered a single 50 mg dose of avitriptan capsule under fasting conditions and 5 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dee354f5e41dc8dfadd126e106e31df1
https://pubmed.ncbi.nlm.nih.gov/9569997
https://pubmed.ncbi.nlm.nih.gov/9569997
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(7)
Avitriptan is a new 5-HT1-like agonist with abortive antimigraine properties. The study was conducted to characterize the pharmacokinetics, absolute bioavailability, and disposition of avitriptan after intravenous (iv) and oral administrations of [14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d397a61580528a6271461ace867fb12f
https://pubmed.ncbi.nlm.nih.gov/9224783
https://pubmed.ncbi.nlm.nih.gov/9224783
Autor:
N R, Srinivas, R S, Weiner, W C, Shyu, J D, Calore, D, Tritschler, L K, Tay, J S, Lee, D S, Greene, R H, Barbhaiya
Publikováno v:
Journal of pharmaceutical sciences. 85(3)
Three skin-intact mice in each group received a single 0.07-, 0.29-, or 0.57-mg dose of CTLA4Ig intravenously (i.v.). Three skin-grafted mice received a single 0.29-mg dose i.v. and another three skin-grafted mice received a 0.29-mg dose once daily f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8e725f41a2e2ba3e7744a614eec11a0
https://pubmed.ncbi.nlm.nih.gov/8699332
https://pubmed.ncbi.nlm.nih.gov/8699332
Publikováno v:
Biopharmaceuticsdrug disposition. 17(2)
The objective of this study was to assess the effect of food on the pharmacokinetics of nefazodone (NEF). A group of 24 healthy adult male volunteers received a single 200 mg dose of NEF under fasting conditions as well as 5 min after a high-fat brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8131e3fa394538056c3b32e715a15c35
https://pubmed.ncbi.nlm.nih.gov/8907720
https://pubmed.ncbi.nlm.nih.gov/8907720
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(1)
The pharmacokinetics and disposition of nefazodone (NEF) were investigated after administration of intravenous (iv) and oral (po) doses to nine healthy men. All volunteers were administered a 5-mg dose of [14C]NEF by iv infusion on study day 1, and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd22565cd312e73881cbedf5e8e125b3
https://pubmed.ncbi.nlm.nih.gov/8825195
https://pubmed.ncbi.nlm.nih.gov/8825195
Publikováno v:
Pharmaceutical research. 12(11)
The absorption and disposition of nefazodone (NEF) and its metabolites hydroxynefazodone (HO-NEF), m-chlorophenylpiperazine (mCPP) and triazole dione (dione) were assessed in 10 healthy subjects following infusion of NEF solution into the proximal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bd781221264ea0b0f8114a15ab74aa6
https://pubmed.ncbi.nlm.nih.gov/8592675
https://pubmed.ncbi.nlm.nih.gov/8592675