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pro vyhledávání: '"D S, Dougall"'
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(8)
A population of CD8+ CTL can be generated in vitro in the presence of anti-CD8 mAb. Due to their apparent high avidity characteristic, these anti-CD8-resistant CD8+ CTL may have important functional in vivo roles in graft rejection, and may be import
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(6)
Almost all conventional CD8+ CTL and their CD8+ precursors are inhibited by anti-CD8 mAb. This requirement for CD8 function reflects both an avidity-augmentation role and a signal-transduction role for CD8 on T cells. We have, however, previously ide