Výsledky vyhledávání - "D S, Dimitrov"

Enhancement of human immunodeficiency virus type 1 envelope-mediated fusion by a CD4-gp120 complex-specific monoclonal antibody

Autor: G Denisova, C C Broder, Shirley Lee, Jody Manischewitz, J M Gershoni, Keith Peden, Hana Golding, D S Dimitrov

Publikováno v: Journal of Virology. 71:6037-6043

The entry of human immunodeficiency virus type 1 (HIV-1) into cells is initiated by binding of the viral glycoprotein gp120-gp41 to its cellular receptor CD4. The gp120-CD4 complex formed at the cell surface undergoes conformational changes that may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48211159007a606ab74342e2c316ea8f
https://doi.org/10.1128/jvi.71.8.6037-6043.1997

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The SARS-CoV S glycoprotein

Autor: X. Xiao, D. S. Dimitrov

Publikováno v: Cellular and Molecular Life Sciences

The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. Recent rapid advances

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc78038481e9cdb0fb4d1dd958768f0a
https://doi.org/10.1007/s00018-004-4257-y

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Phorbol ester-induced down modulation of tailless CD4 receptors requires prior binding of gp120 and suggests a role for accessory molecules

Autor: Hana Golding, D S Dimitrov, J Robinson, C C Broder, S Fabian, Dan R. Littman, C K Lapham, Jody Manischewitz

Publikováno v: Journal of Virology. 69:6140-6148

The entry of human immunodeficiency virus type 1 into cells proceeds via a fusion mechanism that is initiated by binding of the viral glycoprotein gp120-gp41 to its cellular receptor CD4. Species- and tissue-specific restrictions to viral entry sugge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5700954dbd33921ae9bb4b45c55de1b7
https://doi.org/10.1128/jvi.69.10.6140-6148.1995

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Synergistic inhibition of human immunodeficiency virus type 1 envelope glycoprotein-mediated cell fusion and infection by an antibody to CD4 domain 2 in combination with anti-gp120 antibodies

Autor: D S Dimitrov, N Mulrey, R Blumenthal, Linda C. Burkly

Publikováno v: Journal of Virology. 69:4267-4273

Antibodies to several epitopes of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (gp120-gp41) can synergize in inhibiting HIV-1 infection. In the present study we tested the ability of a monoclonal antibody (MAb), 5A8, which in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1814f65026e2c1924de38a7ba3d01ee5
https://doi.org/10.1128/jvi.69.7.4267-4273.1995

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