Výsledky vyhledávání

Putting more genetics into genetic algorithms

Autor: D S, Burke, K A, De Jong, J J, Grefenstette, C L, Ramsey, A S, Wu

Publikováno v: Evolutionary computation. 6(4)

The majority of current genetic algorithms (GAs), while inspired by natural evolutionary systems, are seldom viewed as biologically plausible models. This is not a criticism of GAs, but rather a reflection of choices made regarding the level of abstr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4dc199827405bba8dfd69648ea70620
https://pubmed.ncbi.nlm.nih.gov/10030470

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Size and duration of zidovudine benefit in 1003 HIV-infected patients: U.S. Army, Navy, and Air Force natural history data. Military Medical Consortium for Applied Retroviral Research

Autor: L I, Gardner, S H, Harrison, C W, Hendrix, S P, Blatt, K F, Wagner, R C, Chung, R W, Harris, D L, Cohn, D S, Burke, D L, Mayers

Publikováno v: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. 17(4)

The study's objectives were to determine the size and duration of benefits of early versus delayed versus late treatment with zidovudine (ZDV) on disease progression and mortality in HIV-infected patients, and whether patients rapidly progressing bef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9456b9e3f197abd8aa3dbcf7b94e1da5
https://pubmed.ncbi.nlm.nih.gov/9525436

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HIV-1 genetic diversity

Autor: F E, McCutchan, M O, Salminen, J K, Carr, D S, Burke

Publikováno v: AIDS (London, England). 10

HIV-1 evolves by rapid mutation and by recombination, both processes actively contributing to its genetic diversity. Most of the multiple genetic subtypes and intersubtype recombinations of HIV-1 that comprise the global pandemic have not been charac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d3a541a77aec89fafe800ceb80a7264
https://pubmed.ncbi.nlm.nih.gov/8970707

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Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group

Autor: J R, Mascola, S W, Snyder, O S, Weislow, S M, Belay, R B, Belshe, D H, Schwartz, M L, Clements, R, Dolin, B S, Graham, G J, Gorse, M C, Keefer, M J, McElrath, M C, Walker, K F, Wagner, J G, McNeil, F E, McCutchan, D S, Burke

Publikováno v: The Journal of infectious diseases. 173(2)

Phase I studies of volunteers not infected with human immunodeficiency virus type 1 (HIV-1) have shown that immunization with envelope subunit vaccine products elicits antibodies that neutralize laboratory-adapted (prototype) HIV-1 strains in vitro.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b66cb4aed46df8c655ec02ef12440b28
https://pubmed.ncbi.nlm.nih.gov/8568294

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The U.S. Army HIV testing program: the first decade

Autor: A E, Brown, J F, Brundage, J P, Tomlinson, D S, Burke

Publikováno v: Military medicine. 161(2)

In response to the human immunodeficiency virus (HIV) epidemic, the U.S. military established comprehensive policies to protect individual and public health and to assure military readiness. Central to this effort was the creation of a total-force HI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::506ad9c3aabd7dac2dd39379fb293db6
https://pubmed.ncbi.nlm.nih.gov/8857227

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Lack of induction of antibodies specific for conserved, discontinuous epitopes of HIV-1 envelope glycoprotein by candidate AIDS vaccines

Autor: T C, VanCott, F R, Bethke, D S, Burke, R R, Redfield, D L, Birx

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 155(8)

We examined the humoral immune response in both HIV-1 infected and uninfected volunteers immunized with candidate HIV-1 recombinant envelope subunit vaccines (Genentech gp120IIIB, MicroGeneSys gp160IIIB, or ImmunoAG gp160IIIB). Immunization of both H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9d48a95daa8bf34a428d2d5955d7a4cf
https://pubmed.ncbi.nlm.nih.gov/7561123

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Human immunodeficiency virus type-1 seroconversion trends among young adults serving in the United States Army, 1985-1993. United States Military Medical Consortium for Applied Retroviral Research

Autor: P O, Renzullo, J G, McNeil, Z F, Wann, D S, Burke, J F, Brundage

Publikováno v: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. 10(2)

The direct measurement of the incidence of new infections with the human immunodeficiency virus type 1 (HIV-1) can be made among soldiers because of the routine and periodic nature of HIV-1 testing in the United States Army. Between November 1985 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c528ac1e1a9147b9c3ae95dbe453cf1b
https://pubmed.ncbi.nlm.nih.gov/7552483

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Humoral responses to linear epitopes on the HIV-1 envelope in seropositive volunteers after vaccine therapy with rgp160

Autor: L D, Loomis, C D, Deal, K S, Kersey, D S, Burke, R R, Redfield, D L, Birx

Publikováno v: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. 10(1)

Humoral responses to the HIV-1 envelope were investigated in 30 human volunteers enrolled in a phase I vaccine therapy trial of rgp160 (LAI/LAV) using two techniques that emphasize detection of antibody response against linear (continuous) epitopes:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b4ef9d06911153c6bc97c9745a24ee0
https://pubmed.ncbi.nlm.nih.gov/7544225

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