Zobrazeno 1 - 10
of 595
pro vyhledávání: '"D Roper"'
Autor:
Hadley England, Andrei Herdean, Jennifer Matthews, David J. Hughes, Christine D. Roper, David J. Suggett, Christian R. Voolstra, Emma F. Camp
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Organismal phenotyping to identify fitness traits is transforming our understanding of adaptive responses and ecological interactions of species within changing environments. Here we present a portable Multi-Taxa Phenotyping (MTP) system tha
Externí odkaz:
https://doaj.org/article/15dccc1ad4714687b6dae56eaef6ec51
Autor:
Rachael Scott, David Suggett, Cassidy Hayward, Brent Chatterton, John Edmondson, Johnny Gaskell, Gemma M. Gillette, Lorna Howlett, Emily Monacella, Christine D. Roper, Paige Strudwick, James Unsworth, Michela Veltri, Stephen Woodcock, Emma F. Camp
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
Implementation of coral restoration practices within reef management strategies is accelerating globally to support reef resilience and recovery. However, full costs underpinning restoration project feasibility have historically been underreported ye
Externí odkaz:
https://doaj.org/article/7e4440b235e0427f94ddac6f522b66d7
Practical Synthesis of 7-Bromo-4-chloro-1H-indazol-3-amine: An Important Intermediate to Lenacapavir
Autor:
Naeem Asad, Michael Lyons, Shirley Muniz Machado Rodrigues, Justina M. Burns, Thomas D. Roper, G. Michael Laidlaw, Saeed Ahmad, B. Frank Gupton, Douglas Klumpp, Limei Jin
Publikováno v:
Molecules, Vol 29, Iss 12, p 2705 (2024)
7-Bromo-4-chloro-1H-indazol-3-amine is a heterocyclic fragment used in the synthesis of Lenacapavir, a potent capsid inhibitor for the treatment of HIV-1 infections. In this manuscript, we describe a new approach to synthesizing 7-bromo-4-chloro-1H-i
Externí odkaz:
https://doaj.org/article/58370c2cdc4b470395e7f1bfe475e816
Autor:
Matthew Glace, Cameron Armstrong, Nathan Puryear, Colin Bailey, Roudabeh Sadat Moazeni-Pourasil, Drew Scott, Sherif Abdelwahed, Thomas. D. Roper
Publikováno v:
Molecules, Vol 28, Iss 10, p 4213 (2023)
In this work, a continuous system to produce multi-hundred-gram quantities of aryl sulfonyl chlorides is described. The scheme employs multiple continuous stirred-tank reactors (CSTRs) and a continuous filtration system and incorporates an automated
Externí odkaz:
https://doaj.org/article/c47eecde8d954146866e25520e95d673
Autor:
Drew Scott, Naomi E. B. Briggs, Anna Formosa, Annessa Burnett, Bimbisar Desai, Greg Hammersmith, Kersten Rapp, Gerard Capellades, Allan S. Myerson, Thomas D. Roper
Publikováno v:
Organic Process Research & Development. 27:148-158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d861ba9f143effa3e38543f77ddae0d9
https://doi.org/10.1021/acs.oprd.2c00317
https://doi.org/10.1021/acs.oprd.2c00317
Publikováno v:
Reaction Chemistry & Engineering. 8:1032-1042
Mitigation of failure modes in the continuous synthesis (CS) of a drug substance (DS) has the potential to widen the adoption of continuous manufacturing (CM) technologies by the pharmaceutical industry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::609455fd57de09423e7760282b9e5d12
https://doi.org/10.1039/d2re00476c
https://doi.org/10.1039/d2re00476c
Autor:
Gennady Dvoryanchikov, Damian Hernandez, Jennifer K. Roebber, David L. Hill, Stephen D. Roper, Nirupa Chaudhari
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Characterization of gustatory neural pathways has suffered due to a lack of molecular markers. Here, the authors report single cell RNA sequencing and unbiased transcriptome analyses to reveal major distinctions between gustatory and somatosensory ne
Externí odkaz:
https://doaj.org/article/3c1a5bf7784f470b8279df82b8691fd6
Publikováno v:
Journal of Flow Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::189a22401e58f796cb3727e5472a1ef7
https://doi.org/10.1007/s41981-023-00266-0
https://doi.org/10.1007/s41981-023-00266-0
Autor:
Anna Formosa, Brian J. Marquardt, Luke Rogers, Yuma Miyai, Cameron Armstrong, Thomas D. Roper
Publikováno v:
Organic Process Research & Development. 25:2707-2717
The strategies and experimental methods for implementation of process analytical technology (PAT) on the mobile pharmaceutical manufacturing system, Pharmacy on Demand (PoD), are discussed. With mu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44f89444074ca8a6b5f1c1582fab326
https://doi.org/10.1021/acs.oprd.1c00299
https://doi.org/10.1021/acs.oprd.1c00299
Autor:
Steven D. Roper
Publikováno v:
Human Rights Review. 23:447-449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1121369de13d022ed6c85f57879bc4c8
https://doi.org/10.1007/s12142-022-00667-z
https://doi.org/10.1007/s12142-022-00667-z