Zobrazeno 1 - 10
of 1 024
pro vyhledávání: '"D Rennert"'
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
B cell lymphoma therapy has been transformed by CD19-targeting cellular therapeutics that induce high clinical response rates and impressive remissions in relapsed and refractory patients. However, approximately half of all patients who respond to CD
Externí odkaz:
https://doaj.org/article/26b6ad8375a14924a7d9b11e52588224
Autor:
Christine Ambrose, Lihe Su, Lan Wu, Fay J Dufort, Thomas Sanford, Alyssa Birt, Benjamin J Hackel, Andreas Hombach, Hinrich Abken, Roy R Lobb, Paul D Rennert
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247701 (2021)
Successful CAR T cell therapy for the treatment of solid tumors requires exemplary CAR T cell expansion, persistence and fitness, and the ability to target tumor antigens safely. Here we address this constellation of critical attributes for successfu
Externí odkaz:
https://doaj.org/article/79b29881299c40a5997a27b51c18789e
Abstract 2759: CAR-T engager proteins for the treatment of B cell cancers and acute myeloid leukemia
Publikováno v:
Cancer Research. 82:2759-2759
Chimeric Antigen Receptor T cells targeting malignancies expressing CD19 (CAR19) have been widely successful, with products approved to treat B cell lymphomas (NHL) and B cell leukemia. A major limitation of CAR19 therapy is the steep relapse rate wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef7538d2f12d1c868ee9f65e1e02b023
https://doi.org/10.1158/1538-7445.am2022-2759
https://doi.org/10.1158/1538-7445.am2022-2759
Autor:
Stefano Angiari, Gabriela Constantin, Sheng Xiao, Vittorina Della Bianca, Vijay K. Kuchroo, Enrica Caterina Pietronigro, Simona Budui, Barbara Rossi, Tiziano Donnarumma, Paul D. Rennert, Elena Zenaro, Carlo Laudanna, José M. Casasnovas, Lara Toffali, Gennj Piacentino, Silvia Dusi
Publikováno v:
Immunity
SummarySelectins play a central role in leukocyte trafficking by mediating tethering and rolling on vascular surfaces. Here we have reported that T cell immunoglobulin and mucin domain 1 (TIM-1) is a P-selectin ligand. We have shown that human and mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab1adf79e58c1057336cb04815d4428
https://doi.org/10.1016/j.immuni.2014.03.004
https://doi.org/10.1016/j.immuni.2014.03.004
Publikováno v:
Das Gesundheitswesen. 76:847-855
In Deutschland haben schon in den 1970er Jahren mehrere Selbsthilfeverbande Krebskranker damit begonnen, Patientenbesuche im Krankenhaus fur Krebskranke durchzufuhren. Bisher waren die Gesprache zwischen Patienten und Besuchsdienstmitarbeitern noch n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dcaec5cd3d55af1e16afb8b36bbfaaa
https://doi.org/10.1055/s-0034-1366984
https://doi.org/10.1055/s-0034-1366984
Autor:
Paul D. Rennert
Cancer care is undergoing a radical transformation as novel technologies are directed toward new treatments and personalized medicine. The most dramatic advances in the treatment of cancer have come from therapeutics that augment the immune response
Publikováno v:
Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin. 23:292-300
Die Studie untersucht den Zusammenhang zwischen Merkmalen des sozialen Netzwerkes bei Rehabilitanden mit muskuloskelettalen Erkrankungen und der Sportaktivitat des Rehabilitanden 3 Monate nach Reha-Ende. Die vorliegende Studie ist als multizentrische
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17c63a11912a8934c141dcbf87194fd
https://doi.org/10.1055/s-0033-1355346
https://doi.org/10.1055/s-0033-1355346
Publikováno v:
Journal of Virology. 87:8327-8341
The cell surface receptor T cell immunoglobulin mucin domain 1 (TIM-1) dramatically enhances filovirus infection of epithelial cells. Here, we showed that key phosphatidylserine (PtdSer) binding residues of the TIM-1 IgV domain are critical for Ebola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86a12db49f3b251ed24f9ae263d843a
https://doi.org/10.1128/jvi.01025-13
https://doi.org/10.1128/jvi.01025-13
Autor:
Elizabeth Stepniak, Paul B. Rothman, Judit Knisz, John D. Colgan, Melody Singh, Paul D. Rennert, Geri L. Traver, Miranda L. Curtiss, Natalie Manhica, Bruce S. Hostager
Publikováno v:
Molecular Immunology. 48:1424-1431
The gene encoding T cell immunoglobulin and mucin domain-1 (TIM-1) is linked to atopy and asthma susceptibility in mice and humans. TIM-1 is a transmembrane protein expressed on activated lymphocytes and appears to have a role as a co-stimulatory rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed918f313da186f08bd576aed0a074a3
https://doi.org/10.1016/j.molimm.2011.03.023
https://doi.org/10.1016/j.molimm.2011.03.023
Autor:
Paul B. McCray, Kathrina Quinn, Patrick L. Sinn, Robert A. Davey, David K. Meyerholz, Andrew S. Kondratowicz, Wendy Maury, Sven Moller-Tank, Robert F. Mullins, Lindsay M Sandersfeld, Melodie L. Weller, Paul D. Rennert, Melinda A. Brindley, John A. Chiorini, Nicholas J. Lennemann, Catherine L. Hunt
Publikováno v:
Proceedings of the National Academy of Sciences
The glycoproteins (GP) of enveloped viruses facilitate entry into the host cell by interacting with specific cellular receptors. Despite extensive study, a cellular receptor for the deadly filoviruses Ebolavirus and Marburgvirus has yet to be identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9e3abb862e97dcae0853c8262514a9