Zobrazeno 1 - 10
of 11
pro vyhledávání: '"D R Vlock"'
Autor:
J M, Kirkwood, R A, Mascari, H D, Edington, M S, Rabkin, R S, Day, T L, Whiteside, D R, Vlock, J M, Shipe-Spotloe
Publikováno v:
Cancer. 88(12)
Antitumor effects of antibodies against ganglioside antigens of melanoma have been reported, but neither optimal doses nor mechanisms have been established.This Phase IB trial of the murine immunoglobulin IgG(3) monoclonal antibody R(24) against disi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a0dddf1d15fdcca0f398beb1cdd2a6b
https://pubmed.ncbi.nlm.nih.gov/10870051
https://pubmed.ncbi.nlm.nih.gov/10870051
Autor:
M J, Chang, W D, Yu, L M, Reyno, R A, Modzelewski, M J, Egorin, K, Erkmen, D R, Vlock, P, Furmanski, C S, Johnson
Publikováno v:
Cancer research. 54(20)
We have previously demonstrated that the cytokine interleukin 1 alpha (IL-1 alpha) significantly potentiates the antitumor activity of a variety of chemotherapeutic agents, including cisplatin (cDDP). In studies described here, we examined the potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5faf6ce51abaefd5fdb6e477d565fac9
https://pubmed.ncbi.nlm.nih.gov/7923169
https://pubmed.ncbi.nlm.nih.gov/7923169
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 11(12)
PURPOSE To evaluate the correlation between the presence and titer of host-derived antibody reactivity, circulating immune complexes, and clinical course and prognosis in patients with squamous cell carcinoma of the head and neck (SCCHN). MATERIALS A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263d05ad9d66a64999fdf6830f12a3f6
https://pubmed.ncbi.nlm.nih.gov/8164034
https://pubmed.ncbi.nlm.nih.gov/8164034
Autor:
John M. Kirkwood, H. Jones, E. A. Saria, R. Schwartz, Marc S. Ernstoff, D. R. Vlock, N. Wedel, K. Selvaggi, S. Ackerman
Publikováno v:
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy. 13(3)
XOMAZYME-Mel (XMMME-001-RTA) is an immunoconjugate comprised of ricin A chain conjugated to a murine monoclonal antibody directed against high molecular weight melanoma antigens. Although not necessarily related to increased toxicity or decreased eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abed6df7daca87bd692c334729162ec
https://pubmed.ncbi.nlm.nih.gov/8471594
https://pubmed.ncbi.nlm.nih.gov/8471594
Autor:
D R, Vlock
Publikováno v:
Hematology/oncology clinics of North America. 5(4)
The role of the immune system in the pathogenesis and treatment of cancer remains to be determined. Impairment of humoral and cellular immunity has been associated with various factors implicated in head and neck cancer--tobacco, alcohol, and malnutr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae8603460c8f5f5dbcfed6f70fe48203
https://pubmed.ncbi.nlm.nih.gov/1716250
https://pubmed.ncbi.nlm.nih.gov/1716250
Autor:
D R, Vlock
Publikováno v:
Immunology series. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::034e882b8814dfb779ab4365e023436e
https://pubmed.ncbi.nlm.nih.gov/2151623
https://pubmed.ncbi.nlm.nih.gov/2151623
Autor:
J M Kirkwood, D R Vlock
Publikováno v:
Journal of Clinical Investigation. 76:849-854
The low titer and incidence of autologous antibody to melanoma has hampered its evaluation. Through acid dissociation and ultrafiltration of serum, we have been able to augment the autologous immune response in 9 of 10 patients studied. This result s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57b7391c8118dbd3a670dd09777c6a4
https://doi.org/10.1172/jci112042
https://doi.org/10.1172/jci112042
Publikováno v:
Cancer. 49(11)
Malignant melanoma is considered unresponsive to conventional radiation therapy when it is delivered at a daily dose rate of 130--300 rad/fraction. Previous studies have suggested that this is in part due to a large shoulder on the radiation survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64ea9b3a68d14bd44dfd37d814edeceb
https://pubmed.ncbi.nlm.nih.gov/7074545
https://pubmed.ncbi.nlm.nih.gov/7074545
Autor:
J M, Kirkwood, D R, Vlock
Publikováno v:
Cancer research. 44(9)
Sera of 22 individuals were examined for immunoglobulin M (IgM) and immunoglobulin G (IgG) antibody to autologous cultured tumor cells. Reactive native IgM was detected by immune adherence in four, and IgG by Protein A hemadsorption in five, sera. Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28583e932adfe232f82984490ef27ef3
https://pubmed.ncbi.nlm.nih.gov/6744327
https://pubmed.ncbi.nlm.nih.gov/6744327
Publikováno v:
Cancer research. 49(6)
Serum antibody reactivity to squamous cell carcinoma of the head and neck (SCCHN) was evaluated in 41 autologous serum-tumor cell line combinations using the protein A hemadsorption assay. Autologous antibody reactivity (median titer of 1:4) was dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76280c823ee987944ed8d5304edbd7f9
https://pubmed.ncbi.nlm.nih.gov/2924293
https://pubmed.ncbi.nlm.nih.gov/2924293