Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D R McLachlan"'
Autor:
C A, Mizzen, D R, McLachlan
Publikováno v:
Electrophoresis. 21(12)
Existing methods for the analysis of histone H1 by capillary electrophoresis (CE) employ acidic buffers (pH3.0) to suppress silanol ionization and minimize the loss of these extremely basic proteins by adsorption to capillary walls. Here we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ceebb4fa807db716ca3fc6bbc755e1a
https://pubmed.ncbi.nlm.nih.gov/10939446
https://pubmed.ncbi.nlm.nih.gov/10939446
Autor:
P, St George-Hyslop, E, Rogaeva, J, Huterer, T, Tsuda, J, Santos, J L, Haines, K, Schlumpf, E I, Rogaev, Y, Liang, D R, McLachlan
Publikováno v:
American journal of human genetics. 55(1)
A locus for Machado-Joseph disease (MJD) has recently been mapped to a 30-cM region of chromosome 14q in five pedigrees of Japanese descent. MJD is a clinically pleomorphic neurodegenerative disease that was originally described in subjects of Azorea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eeafafef9911c83ecec94729e843ffc9
https://pubmed.ncbi.nlm.nih.gov/8023841
https://pubmed.ncbi.nlm.nih.gov/8023841
Publikováno v:
Basic and Clinical Aspects of Neuroscience ISBN: 9783540571568
In eukaryotic nuclei, the expression of genes is a complex series of events in which information encoded in the DNA molecule is transcribed into ribonucleic acid (RNA) and translated into proteins essential for normal cellular function. The first ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::743d06c1a0480874a4fb96630a9ca647
https://doi.org/10.1007/978-3-642-78458-3_4
https://doi.org/10.1007/978-3-642-78458-3_4
Publikováno v:
Therapeutic drug monitoring. 15(6)
Drug trials designed to modify the progression of Alzheimer's disease (AD) have required the development of mental state and behavior evaluation instruments that are sensitive to cognitive decline and measure skills useful in everyday living. We desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46f0a2af134a4aeccc15dab95e193413
https://pubmed.ncbi.nlm.nih.gov/8122302
https://pubmed.ncbi.nlm.nih.gov/8122302
Autor:
D. R. McLachlan, Joan Massiah
Publikováno v:
The Vulnerable Brain and Environmental Risks ISBN: 9781461364672
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f4542de86a1b46ac86fb1d8a0767895
https://doi.org/10.1007/978-1-4615-3330-6_4
https://doi.org/10.1007/978-1-4615-3330-6_4
Publikováno v:
Ciba Foundation symposium. 169
Known risk factors for Alzheimer's disease (AD) are few and insufficient knowledge is available to recommend steps to reduce AD in our ageing populations. Although not 'the cause', considerable evidence implicates human ingestion of aluminium as a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d57b793a17e92768ea94369122a6dd7
https://pubmed.ncbi.nlm.nih.gov/1490430
https://pubmed.ncbi.nlm.nih.gov/1490430
Publikováno v:
Advances in experimental medicine and biology. 291
Our laboratory has measured mRNA pool sizes in neocortex afflicted with Alzheimer's disease (AD). We have observed a repression of gene expression in the temporal and parietal regions compared to age-matched control neocortex. These changes in messen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e0ba506e0738a610362975f556b5069
https://pubmed.ncbi.nlm.nih.gov/1927687
https://pubmed.ncbi.nlm.nih.gov/1927687
Publikováno v:
The International journal of neuroscience. 55(2-4)
Total RNA was extracted from human brain temporal and parietotemporal neocortical grey matter with postmortem intervals (PMI) of up to 13.5 hours. The integrity and rank abundance of heterogeneous nuclear RNA (HnRNA) and messenger RNA (mRNA) were ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62747a050dc077fb69330ac6bdb69000
https://pubmed.ncbi.nlm.nih.gov/2084053
https://pubmed.ncbi.nlm.nih.gov/2084053
Autor:
D M, Nicholls, D R, McLachlan
Publikováno v:
Basic life sciences. 55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c68c81f32122a4e3f2c032681ab72e81
https://pubmed.ncbi.nlm.nih.gov/2088274
https://pubmed.ncbi.nlm.nih.gov/2088274
Autor:
D. T. Peterson, D. R. Mclachlan
Publikováno v:
Metallurgical Transactions A. 6:1359-1366
The effect of nitrogen in solid solution on the plastic deformation of polycrystalline thorium was studied by measuring the flow stress from 4.2 K to 773 K at several strain rates. Nitrogen was found to behave similarly to carbon in thorium and incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e9ebb7b8742f6109f5412916faae954
https://doi.org/10.1007/bf02641929
https://doi.org/10.1007/bf02641929