Zobrazeno 1 - 10
of 53
pro vyhledávání: '"D R Kaplan"'
Autor:
Loen M. Hansford, T S-K Wan, D R Kaplan, S-T Lau, G C-F Chan, E S-W Ngan, Kenneth K. Y. Wong, P K-H Tam, W. K. Chan
Publikováno v:
Oncogene. 34:1019-1034
High cellular heterogeneity within neuroblastomas (NBs) may account for the non-uniform response to treatment. c-KIT(+) cells are frequently detected in NB, but how they influence NB behavior still remains elusive. Here, we used NB tumor-initiating c
Testosterone is a sex hormone involved in brain maturation via multiple molecular mechanisms. Previous human studies described age-related changes in the overall volume and morphological properties of white matter during male puberty. Based on this w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359a66d53e11861874b26a5cae1b49e2
https://europepmc.org/articles/PMC4461529/
https://europepmc.org/articles/PMC4461529/
Autor:
M Hang, D R Kaplan, Loen M. Hansford, Loretta Lau, Sylvain Baruchel, Meredith S. Irwin, L S Cheng
Publikováno v:
Oncogene. 26:1920-1931
Cyclooxygenase-2 (COX-2) is upregulated in many tumors including neuroblastoma, and its overexpression has been implicated in resistance to p53-dependent apoptosis. Although p53 is rarely mutated in neuroblastoma, the p53 protein is rendered inactive
Autor:
D. K. Morrison, Philip N. Tsichlis, Thomas F. Franke, Ketaki Datta, Erica A. Golemis, D. R. Kaplan, Antonios M. Makris, Sung-Il Yang, Tung O. Chan
Publikováno v:
Molecular and Cellular Biology. 15:2304-2310
The cytoplasmic serine-threonine protein kinase coded for by the c-akt proto-oncogene features a protein kinase C-like catalytic domain and a unique NH2-terminal domain (AH domain). The AH domain is a member of a domain superfamily whose prototype wa
Publikováno v:
The Journal of Experimental Medicine
Increasing evidence suggests that the nervous system is involved in allergic inflammation. One of the potential regulatory molecules of the neuroimmune system is nerve growth factor (NGF). Recent studies from our group demonstrated the presence of a
Autor:
A. G. Kartsatos, D. R. Kaplan
Publikováno v:
Journal of Optimization Theory and Applications. 81:121-141
Some results are given involving the controllability of a nonlinear evolution equation of the formx′(t)+A(t,u(t))x(t)=B(t)u(t). The underlying space is a real Banach space with uniformly convex dual space. A method involving ranges of sums of two n
Publikováno v:
The Journal of Neuroscience. 14:1542-1554
The response of brain tissue to neurotrophins during rat development was examined using a novel in vitro assay for Trk/neurotrophin receptor activity. In this assay, brain tissues were exposed to neutrophins and ligand-induced Trk tyrosine phosphoryl
Autor:
D R, Kaplan
Publikováno v:
American journal of botany. 88(10)
As a scientific discipline, plant morphology is 211 yr old, originated by Goethe in 1790. It is a discipline that has largely been Germanic in practice. Because it took its origins from the study of the natural history of plants and the United States
Publikováno v:
Molecular and Cellular Biology. 13:2203-2213
To elucidate the signal transduction mechanisms used by ligands that induce differentiation and the cessation of cell division, we utilized p13suc1-agarose, a reagent that binds p34cdc2/cdk2. By using this reagent, we identified a 78- to 90-kDa speci
Publikováno v:
Journal of Biological Chemistry. 267:17472-17477
We investigated the involvement of phosphatidylinositol 3-kinase (PtdIns 3-kinase) in the initiation of signal transduction by nerve growth factor (NGF) in the rat pheochromocytoma PC12 cell line. PtdIns 3-kinase catalyzes the formation of phosphoino