Zobrazeno 1 - 10
of 11
pro vyhledávání: '"D R Hemenway"'
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 10:167-176
Parietal pleural plaques and visceral pleural fibrosis are well-recognized stigmata of occupational asbestos exposure. However, their pathogenesis is poorly understood. Conceivably, phagocytosis of asbestos fibers by pleural mesothelial cells may sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121e275fc8b088986e748b02189a1ea0
https://doi.org/10.1165/ajrcmb.10.2.8110473
https://doi.org/10.1165/ajrcmb.10.2.8110473
Publikováno v:
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 20
Silicosis is characterized by mononuclear cell aggregation with mineral particles and fibrosis. Lymphocytes are abundant in these lesions. We exposed inbred strains of mice to a respirable aerosol of cristobalite silica (70 mg/m3, 5 h/d, 12 d) or sha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a338abe1bf95e588c78116e868ab429
https://pubmed.ncbi.nlm.nih.gov/11570674
https://pubmed.ncbi.nlm.nih.gov/11570674
Publikováno v:
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 17(2)
The cytokines interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNFalpha), derived from macrophages and other cells, may promote mononuclear cell inflammation and fibrosis in pulmonary silicosis. C3H/HeN mice were exposed to control air o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d07aec586aa2f156da975257c3d6e07
https://pubmed.ncbi.nlm.nih.gov/9546746
https://pubmed.ncbi.nlm.nih.gov/9546746
Publikováno v:
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 17(2)
Experimental silicosis allows study of the mechanisms of lung injury, inflammation, and fibrosis. Inbred mice are an attractive species in which to study these mechanisms because of recent progress in murine immunology, molecular biology, and genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e33a91c294e3115759a51bb646ca5a0
https://pubmed.ncbi.nlm.nih.gov/9546745
https://pubmed.ncbi.nlm.nih.gov/9546745
Publikováno v:
Regional immunology. 5(3-4)
Transforming growth factor-alpha (TGF-alpha) a cytokine having potent mitogenic activity for epithelial and mesenchymal cells, may play a role in the lung remodeling of silicosis. Lung macrophages are among the major cells producing TGF-alpha in a lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::365547387fa227571ad48adef5b3f510
https://pubmed.ncbi.nlm.nih.gov/8240939
https://pubmed.ncbi.nlm.nih.gov/8240939
Publikováno v:
Chest. 103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b733179d2dd4e90616678e420d406427
https://pubmed.ncbi.nlm.nih.gov/8428530
https://pubmed.ncbi.nlm.nih.gov/8428530
Publikováno v:
Research report (Health Effects Institute). (53)
Knowledge about the health effects of exposure to formaldehyde associated with automotive emissions is of pivotal importance in the risk assessment of this agent. Mobile sources emit many combustion-derived pollutants, including formaldehyde, in asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7243fdbcad8f649ddbf0a247d33fbf8
https://pubmed.ncbi.nlm.nih.gov/1466836
https://pubmed.ncbi.nlm.nih.gov/1466836
Publikováno v:
The American journal of pathology. 136(4)
Alpha-cristobalite causes pulmonary interstitial disease in humans and experimental animals. Aerosol exposure of rats to cristobalite for 8 days results in early and sustained alveolar type II cell hyperplasia in areas of inflammation characterized b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e2ec6d78be9119507849470426ce64a
https://pubmed.ncbi.nlm.nih.gov/2158238
https://pubmed.ncbi.nlm.nih.gov/2158238
Publikováno v:
Chest. 103:120S-121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eed5aece4ce91807a076afe863119100
https://doi.org/10.1378/chest.103.2.120s
https://doi.org/10.1378/chest.103.2.120s
Publikováno v:
The American journal of pathology. 134(6)
Cristobalite is a crystalline silicon dioxide that elicits pulmonary inflammation and fibrosis in humans and experimental animals. Exposure of rats to aerosols of respirable cristobalite for 8 days led to a rapid influx of neutrophils and macrophages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86d9053dc49c27fdccba3cbe9635d4e6
https://pubmed.ncbi.nlm.nih.gov/2547319
https://pubmed.ncbi.nlm.nih.gov/2547319