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pro vyhledávání: '"D R Guay"'
Autor:
D R, Guay
Publikováno v:
Pharmacotherapy. 18(6)
Repaglinide is a new, short-acting, insulin-releasing agent recently approved for the monotherapy of type 2 diabetes mellitus, and in combination with metformin in patients failing repaglinide or metformin monotherapy. Repaglinide appears to trigger
Publikováno v:
Pharmacotherapy. 16(4)
Intravenous erythromycin has recently been associated with significant QTc interval prolongation, torsades de pointes, and sudden cardiac death. The prolonged the QTc interval attributed to erythromycin typically is associated with rapid infusion rat
Antihypertensive drug use in the long-term care facility: a pilot study and review of the literature
Publikováno v:
Pharmacotherapy. 15(6)
The overuse and cost of drugs in long-term care facilities are of significant concern. To quantify potential overuse of antihypertensive agents, we conducted a retrospective chart review in four long-term care facilities. We analyzed data in 550 pati
Publikováno v:
Archives of internal medicine. 152(2)
Rapid index case treatment and amantadine prophylaxis were implemented in two nursing homes exposed to influenza A. Facility A had no isolation of cases, and 18 of 22 cases occurred after amantadine hydrochloride therapy was initiated. Three patients
Autor:
D R, Guay
Publikováno v:
Pharmacotherapy. 12(6 Pt 2)
Over the past decade, the quinolone antimicrobial class has enjoyed a renaissance with the emergence of the fluoroquinolone subclass. Norfloxacin, ciprofloxacin, ofloxacin, enoxacin, and lomefloxacin have the advantages of broad antimicrobial activit
Publikováno v:
Diagnostic microbiology and infectious disease. 15(1)
The in vitro and in vivo spectrum of antibacterial activity of clarithromycin is summarized and related to its human pharmacokinetics. In vitro studies by several investigators have documented clarithromycin's activity against bacterial agents of res
Publikováno v:
Therapeutic drug monitoring. 13(6)
Characterization of antibiotic pharmacokinetics in patients with renal insufficiency may be complicated by interfering substances within the assay. We compared three different assays for teicoplanin in serum and dialysate of 10 hemodialysis and six c
Autor:
R S Kalil, C A Hirata-Dulas, C A Dinarello, A L Ney, M L Bullock, William F. Keane, C E Halstenson, P K Peterson, D R Guay
Publikováno v:
Journal of the American Society of Nephrology : JASN. 2(4)
The objective of this prospective, randomized, double-blind, placebo-controlled clinical trial was to evaluate the efficacy of adjunctive therapy with iv human immunoglobulin G in reducing the morbidity and mortality associated with acute renal failu
Publikováno v:
Pharmacotherapy. 11(6)
Pharmacokinetic and adverse event profiles of 50- and 100-mg amantadine doses administered daily for up to 21 days for influenza prophylaxis were compared in 82 elderly nursing home residents (mean age 85 yrs, 68% female). We sought to determine if a
Publikováno v:
Clinical pharmacy. 2(2)
The bioavailability and pharmacokinetics of cimetidine were studied following single oral and intravenous doses in subjects with severely impaired renal function (SIRF) and normal renal function (NRF). Eight subjects with NRF and five patients with S