Zobrazeno 1 - 10
of 12
pro vyhledávání: '"D R, Van Wagoner"'
Autor:
Jonathan D. Smith, Mina K. Chung, Meghan McHale, A. M. Gillinov, D. R. Van Wagoner, John Barnard, Julie H. Rennison, Erik Offerman, Christine S. Moravec, Jeffrey Hsu, Sojin Y Wass, Catherine Cantlay, Han Sun
RationaleGenome wide association studies (GWAS) have associated >100 genetic loci with atrial fibrillation (AF), yet the biological pathways of AF remain elusive.ObjectiveTo determine candidate causal genes associated with AF risk loci and their coex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0965184a650e7494145f484056494057
https://doi.org/10.1101/2021.09.20.21263861
https://doi.org/10.1101/2021.09.20.21263861
Autor:
Wei Li, Xin Yu, Laurie Castel, Margaret P. Chandler, D. R. Van Wagoner, Yuanna Cheng, Tracy A. McElfresh, Xiaoqin Chen, Jessica M. Berthiaume
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 301:H1438-H1446
Pathological conditions such as diabetes, insulin resistance, and obesity are characterized by elevated plasma and myocardial lipid levels and have been reported to exacerbate the progression of heart failure (HF). Alterations in cardiomyocyte Ca2+ r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbc12dbbae64bdd4aab3e9a5b889fa86
https://doi.org/10.1152/ajpheart.00440.2011
https://doi.org/10.1152/ajpheart.00440.2011
Autor:
Yuanna Cheng, Igor R. Efimov, Todor N. Mazgalev, Patrick J. Tchou, Gregory A. Kidwell, Gerard J. Fahy, D. R. Van Wagoner
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 272:H2815-H2825
We investigated whether atrioventricular (AV) nodal facilitation is the result of distal AV nodal action potential shortening. Atrial and bundle of His (H) electrograms and microelectrode recordings from proximal and distal AV nodal cells were analyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2271eb00ce745c15baa0abbe061778f3
https://doi.org/10.1152/ajpheart.1997.272.6.h2815
https://doi.org/10.1152/ajpheart.1997.272.6.h2815
Autor:
Y, Cheng, W, Li, T A, McElfresh, X, Chen, J M, Berthiaume, L, Castel, X, Yu, D R, Van Wagoner, M P, Chandler
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 301(4)
Pathological conditions such as diabetes, insulin resistance, and obesity are characterized by elevated plasma and myocardial lipid levels and have been reported to exacerbate the progression of heart failure (HF). Alterations in cardiomyocyte Ca(2+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77cb2a76bb7bcdd69585a6814c1cff72
https://pubmed.ncbi.nlm.nih.gov/21765056
https://pubmed.ncbi.nlm.nih.gov/21765056
Publikováno v:
Journal of Biological Chemistry. 268:27335-27344
The release of arachidonic acid by phospholipases in response to cell surface receptor activation may be an important step in the initiation of inotropic events in cardiac muscle. Endothelin has been shown to activate phospholipase A2 and release ara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21f418ed0ad3d31b2d4d21a063d431c0
https://doi.org/10.1016/s0021-9258(19)74254-9
https://doi.org/10.1016/s0021-9258(19)74254-9
Autor:
D. R. Van Wagoner, A. Kanderian, Patrick M. McCarthy, Robert L. Hamlin, Hitomi Nakayama, Cynthia A. Carnes, John Anthony Bauer, M. K. Chung, S. Pavia, Tomohiro Nakayama, Reshma S. Baliga, Sheng-Fu Piao
Publikováno v:
ResearcherID
Atrial fibrillation (AF), the most common chronic arrhythmia, increases the risk of stroke and is an independent predictor of mortality. Available pharmacological treatments have limited efficacy. Once initiated, AF tends to self-perpetuate, owing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e707108215d0e5b5137f753db2ef2ced
https://pubmed.ncbi.nlm.nih.gov/11557745
https://pubmed.ncbi.nlm.nih.gov/11557745
Autor:
A L, Pond, B K, Scheve, A T, Benedict, K, Petrecca, D R, Van Wagoner, A, Shrier, J M, Nerbonne
Publikováno v:
The Journal of biological chemistry. 275(8)
One form of inherited long QT syndrome, LQT2, results from mutations in HERG1, the human ether-a-go-go-related gene, which encodes a voltage-gated K(+) channel alpha subunit. Heterologous expression of HERG1 gives rise to K(+) currents that are simil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b759f38f314c4d7ac21f6433aadc27a6
https://pubmed.ncbi.nlm.nih.gov/10681594
https://pubmed.ncbi.nlm.nih.gov/10681594
Publikováno v:
Canadian journal of physiology and pharmacology. 76(12)
Voltage-sensitive dyes and imaging techniques have proved to be indispensable tools for use in in vitro electrophysiological studies. To avoid motion artifacts in optical recordings, electromechanical uncouplers such as 2,3-butanedione monoxime (BDM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc68947f4dc8434ce22d94d22177e8be
https://pubmed.ncbi.nlm.nih.gov/10326837
https://pubmed.ncbi.nlm.nih.gov/10326837
Publikováno v:
The American journal of physiology. 271(3 Pt 2)
The modulation of whole cell K+ currents by the alpha 1-adrenergic agonist, phenylephrine, was studied in isolated rat atrial myocytes by use of perforated-patch whole cell recording techniques. The out ward K+ current in these myocytes consists of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d775984e1a90dfe6340b5b28b1cdcf8
https://pubmed.ncbi.nlm.nih.gov/8853328
https://pubmed.ncbi.nlm.nih.gov/8853328
Autor:
D R, Van Wagoner, M, Lamorgese
Publikováno v:
Annals of the New York Academy of Sciences. 723
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9325f05e2d78d7239d23b348dcc325c
https://pubmed.ncbi.nlm.nih.gov/8030893
https://pubmed.ncbi.nlm.nih.gov/8030893