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Aldosterone (mineralocorticoid) equivalent to prednisolone (glucocorticoid) in reversing hearing loss in MRL/MpJ-Fas1pr autoimmune mice

Autor: D R, Trune, J B, Kempton, M, Kessi

Publikováno v: The Laryngoscope. 110(11)

Although the glucocorticoid prednisone is the standard therapy for autoimmune sensorineural hearing loss, what this hormone does in the ear to restore hearing is not known. MRL/MpJ-Fas(lPr) autoimmune mice consistently have shown only stria vasculari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a36364024ae208300ed792a69cad4d60
https://pubmed.ncbi.nlm.nih.gov/11081607

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Twenty-stimulus train for rapid acquisition of auditory brainstem responses in humans

Autor: J A, Henry, S A, Fausti, J B, Kempton, D R, Trune, C R, Mitchell

Publikováno v: Journal of the American Academy of Audiology. 11(2)

This study addressed the clinical need to obtain frequency-specific auditory brainstem responses (ABRs) more rapidly than is currently possible. ABRs were obtained from 20 subjects using two different methods: a conventional method with tone bursts p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d9a3c3e4bf57fbb51eb10f367e1afd9a
https://pubmed.ncbi.nlm.nih.gov/10685677

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Steroid-responsive cochlear dysfunction in the MRL/lpr autoimmune mouse

Autor: R J, Wobig, J b, Kempton, D R, Trune

Publikováno v: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 121(4)

Corticosteroids historically have been used to treat autoimmune sensorineural hearing loss, although little is known of how steroids restore normal inner ear function. Therefore, to identify a potential model for this field of research, this study ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b068b426d9a7e4c50794baf32e38db04
https://pubmed.ncbi.nlm.nih.gov/10504585

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Craniofacial and otic capsule abnormalities in a transgenic mouse strain with a Col2a1 mutation

Autor: B K, Maddox, S, Garofalo, W A, Horton, M D, Richardson, D R, Trune

Publikováno v: Journal of craniofacial genetics and developmental biology. 18(4)

Abnormal craniofacial features of a transgenic mouse model of chondrodysplasia with a type II collagen mutation (Gly574Ser) are described in this report. In addition to a shortened mandible and cleft palate, a misshapen otic capsule was observed. Int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::18e518013a96b42a72cc41a54720576b
https://pubmed.ncbi.nlm.nih.gov/10100048

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Tumor angiogenesis, the p53 antigen, and cervical metastasis in squamous carcinoma of the tongue

Autor: D A, Leedy, D R, Trune, J D, Kronz, N, Weidner, J I, Cohen

Publikováno v: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 111(4)

A more accurate method of detecting nodal disease in squamous cell carcinoma of the tongue is needed so that treatment of the neck with its associated morbidity can safely be reserved for patients who actually have metastatic disease. Tumor angiogene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4dc87d785ead7f822ccb358c7a737ad9
https://pubmed.ncbi.nlm.nih.gov/7524005

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Histologic changes in selenite cortical cataract

Autor: R S, Anderson, D R, Trune, T R, Shearer

Publikováno v: Investigative ophthalmologyvisual science. 29(9)

Massive cortical cataract was produced 15-30 days after a single injection of an overdose of sodium selenite into 14-day-old rats. Most of the cortical cataract appeared to be due to extensive liquefaction of cortical fibers. Water influx, following

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38adbd61ab08b928d443fdc1a4991c68
https://pubmed.ncbi.nlm.nih.gov/3417427

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