Zobrazeno 1 - 5
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pro vyhledávání: '"D R, Plowchalk"'
Publikováno v:
Inhalation Toxicology. 13:377-396
Vinyl acetate is used in the manufacture of many polymers. The Clean Air Act Amendments of 1990 require that an inhalation risk assessment be conducted to assess risks to human health from ambient exposures. Vinyl acetate is a nasal carcinogen in rat
Publikováno v:
Toxicological Sciences. 46:235-246
Physiologically based pharmacokinetic (PBPK) models require estimates of catalytic rate constants controlling the metabolism of xenobiotics. Usually, these constants are derived from whole tissue homogenates wherein cellular architecture and enzyme c
Publikováno v:
Scopus-Elsevier
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On the basis of current knowledge of reproductive biology and toxicology, it is apparent that chemicals affecting reproduction may elicit their effects at a number of sites in both the male and the female reproductive system. This multiplicity of tar
Publikováno v:
Toxicology and applied pharmacology. 116(2)
A physiologically based pharmacokinetic (PBPK) model was developed to describe the disposition of nicotine in the Sprague-Dawley (SD) rat. Parameters for the model were either obtained from the literature (blood flows, organ volumes) or determined ex
Publikováno v:
Physiological chemistry and physics and medical NMR. 19(1)
The contrast and intensity of a magnetic resonance image (MRI) is affected in part by the spin-lattice relaxation time (T1) and spin-spin relaxation time (T2). Certain paramagnetic metal ions can alter these parameters suggesting that they may be use