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pro vyhledávání: '"D R, Moller"'
Autor:
D R Moller, S L Kunkel, Leona Mawhinney, M Strengert, David N O'Dwyer, Seamas C. Donnelly, Emily Hams, Denis C. Shields, Michelle E. Armstrong, Ulla G. Knaus, I Kamal, Ciaran O’Reilly, Aisling Tynan, Cory M. Hogaboam, Gordon Cooke, Padraic G. Fallon, Andrew G. Bowie
Publikováno v:
Articles
BACKGROUND/INTRODUCTION: Sarcoidosis is a multi-systemic disorder of unknown etiology, characterized by the presence of non-caseating granulomas in target organs. In 90% of cases, there is thoracic involvement. Fifty to seventy percent of pulmonary s
Publikováno v:
Immunology. 88:516-523
Sarcoidosis is a multisystem disorder characterized by non-caseating granulomas and the accumulation of CD4+ T cells in involved tissues such as the lung. To evaluate the diversity of the CD4+ T-cell repertoire in this disorder, a detailed clonal ana
Autor:
D R Moller, J D Forman, M C Liu, P W Noble, B M Greenlee, P Vyas, D A Holden, J M Forrester, A Lazarus, M Wysocka, G Trinchieri, C Karp
Publikováno v:
The Journal of Immunology. 156:4952-4960
Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by the expansion of activated oligoclonal CD4+ T cells and macrophages at sites of disease. To investigate the immunopathogenesis of sarcoidosis, we analyzed pattern
Publikováno v:
The Journal of Immunology. 154:1450-1460
Sarcoidosis is a multiorgan granulomatous disorder of unknown etiology characterized by noncaseating granulomas in involved tissues. A positive Kveim-Siltzbach reaction is a granulomatous response to an intradermal injection of a suspension of sarcoi
Autor:
D R, Moller
Publikováno v:
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. 16(1)
Granulomatous inflammation develops under the regulatory influence of cytokines produced by local mononuclear phagocytes, T cells, dendritic cells, fibroblasts, and other local cells. In sarcoidosis, granulomatous inflammation is characterized by dom
Autor:
D R, Moller
Publikováno v:
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. 15(2)
The pathogenesis of sarcoidosis involves activated, cytokine-producing T-cells and macrophages that regulate granulomatous inflammation. At sites of inflammation, T-cells demonstrate reduced surface density of the CD3 component of the T-cell receptor
Autor:
D R, Moller
Publikováno v:
Seminars in respiratory infections. 13(3)
Sarcoidosis is recognized to be a multisystem granulomatous disease characterized by activated, cytokine-producing T cells and macrophages at sites of inflammation. The purpose of this article is to review new evidence concerning the role of T cells
The immunomodulatory properties of thalidomide are currently being exploited therapeutically in conditions as diverse as erythema nodosum leprosum, chronic graft-vs-host disease, rheumatoid arthritis, and sarcoidosis. The relevant mechanism of action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118a85a36e0be54c94c18347105cd7ae
https://doi.org/10.4049/jimmunol.159.10.5157
https://doi.org/10.4049/jimmunol.159.10.5157
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(3)
Sarcoidosis is a multiorgan granulomatous disorder of unknown etiology characterized by noncaseating granulomas in involved tissues. A positive Kveim-Siltzbach reaction is a granulomatous response to an intradermal injection of a suspension of sarcoi
Publikováno v:
The American review of respiratory disease. 134(1)
The natural history of isocyanate-induced asthma is not well documented. We evaluated a patient who developed persistent shortness of breath, wheezing, and cough after a massive exposure to toluene diisocyanate (TDI). Despite no further occupational