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Publikováno v:
ChemInform. 27
Autor:
M G, Banwell, C F, Crasto, C J, Easton, T, Karoli, D R, March, M R, Nairn, P J, O'Hanlon, M D, Oldham, A C, Willis, W, Yue
Publikováno v:
Chemical communications (Cambridge, England). (21)
The ketone (+/-)-5, which embodies the bicyclic core associated with the title tRNA synthetase inhibitors 1 and 2, has been prepared via a three-component coupling reaction involving 2-(hydroxymethyl)cyclopent-2-enone (15), methylamine (6) and propio