Zobrazeno 1 - 10
of 198
pro vyhledávání: '"D Planer"'
Autor:
Gan Zhao, Maria E. Gentile, Lulu Xue, Christopher V. Cosgriff, Aaron I. Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P. Holcomb, Maria C. Basal, Kathleen M. Stewart, Joseph D. Planer, Edward Cantu, Jason D. Christie, Maria M. Crespo, Michael J. Mitchell, Nuala J. Meyer, Andrew E. Vaughan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Inflammation induced by lung infection is a double-edged sword, moderating both anti-viral and immune pathogenesis effects; the mechanism of the latter is not fully understood. Previous studies suggest the vasculature is involved in tissue i
Externí odkaz:
https://doaj.org/article/298e4f96eba74047b28b7e392be57e41
Autor:
Gan Zhao, Maria E. Gentile, Lulu Xue, Christopher V. Cosgriff, Aaron I. Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P. Holcomb, Maria C. Basal, Kathleen M. Stewart, Joseph D. Planer, Edward Cantu, Jason D. Christie, Maria M. Crespo, Michael J. Mitchell, Nuala J. Meyer, Andrew E. Vaughan
Publikováno v:
bioRxiv
Inflammation upon infectious lung injury is a double-edged sword: while tissue-infiltrating immune cells and cytokines are necessary to control infection, these same factors often aggravate injury. Full appreciation of both the sources and targets of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f06f4517047ef22e053a3f66a0fc31b
https://europepmc.org/articles/PMC10245987/
https://europepmc.org/articles/PMC10245987/
Autor:
Joseph D. Planer, Edward E. Morrisey
Publikováno v:
Annual review of pathology.
The mammalian lung has an enormous environmental-epithelial interface that is optimized to accomplish the principal function of the respiratory system, gas exchange. One consequence of evolving such a large surface area is that the lung epithelium is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11aff84c0d6e77665190a35393dfcc1
https://pubmed.ncbi.nlm.nih.gov/36270292
https://pubmed.ncbi.nlm.nih.gov/36270292
Autor:
Susan M. Lin, Ryan Rue, Akansha Goel, Kseniya Obraztsova, Alexander R. Mukhitov, Kanth Swaroop Vanka, Carly J. Smith, Maria C. Basil, Laura T. Ferguson, Joseph D. Planer, Edward Cantu, Grazyna Kwapiszewska, Edward E. Morrisey, Jillian F. Evans, Vera P. Krymskaya
Pulmonary vascular remodeling is the key structural abnormality in pulmonary hypertension (PH). Mechanistic target of rapamycin (mTOR) has long been suspected to play a role in the development of pulmonary vascular remodeling. However, underlying cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da666a5cd4a35e3f11b5da871f4e9bda
https://doi.org/10.1101/2022.10.08.511300
https://doi.org/10.1101/2022.10.08.511300
Autor:
Kazushige Shiraishi, Parisha P. Shah, Michael P. Morley, Claudia Loebel, Garrett T. Santini, Jeremy Katzen, Maria C. Basil, Susan M. Lin, Joseph D. Planer, Edward Cantu, Dakota L. Jones, Ana N. Nottingham, Shanru Li, Fabian L. Cardenas-Diaz, Su Zhou, Jason A. Burdick, Rajan Jain, Edward E. Morrisey
Publikováno v:
Cell. 186:1478-1492.e15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c10e97cc566ed48231c74d57f6c65b3
https://doi.org/10.1016/j.cell.2023.02.010
https://doi.org/10.1016/j.cell.2023.02.010
Akademický článek
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Akademický článek
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Synergy testing of FDA-approved drugs identifies potent drug combinations against Trypanosoma cruzi.
Autor:
Joseph D Planer, Matthew A Hulverson, Jennifer A Arif, Ranae M Ranade, Robert Don, Frederick S Buckner
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e2977 (2014)
An estimated 8 million persons, mainly in Latin America, are infected with Trypanosoma cruzi, the etiologic agent of Chagas disease. Existing antiparasitic drugs for Chagas disease have significant toxicities and suboptimal effectiveness, hence new t
Externí odkaz:
https://doaj.org/article/ba693335c824477fa3bbab1573a1a19d
Autor:
Maria C. Basil, Fabian L. Cardenas-Diaz, Jaymin J. Kathiriya, Michael P. Morley, Justine Carl, Alexis N. Brumwell, Jeremy Katzen, Katherine J. Slovik, Apoorva Babu, Su Zhou, Madison M. Kremp, Katherine B. McCauley, Shanru Li, Joseph D. Planer, Shah S. Hussain, Xiaoming Liu, Rebecca Windmueller, Yun Ying, Kathleen M. Stewart, Michelle Oyster, Jason D. Christie, Joshua M. Diamond, John F. Engelhardt, Edward Cantu, Steven M. Rowe, Darrell N. Kotton, Harold A. Chapman, Edward E. Morrisey
Publikováno v:
Nature
Nature, vol 604, iss 7904
Nature, vol 604, iss 7904
The human lung differs substantially from its mouse counterpart, resulting in a distinct distal airway architecture affected by disease pathology in chronic obstructive pulmonary disease. In humans, the distal branches of the airway interweave with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a4c7583722bacfc4bff991f56e4a69
https://pubmed.ncbi.nlm.nih.gov/35355013
https://pubmed.ncbi.nlm.nih.gov/35355013
Akademický článek
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