Identification of Compound Heterozygous Mutation in HFE Gene in a Child with Cystic Fibrosis: A Case Report with Data on HFE Genetic Variants

Autor: N. Ba Sharahil, M.J. Rock, P.M. Farrell, H.J. Lai, D. Pfeil, P. Modaff, M. Gajapathy, B.M. Wilk, D.M. Brown, E.A. Worthey

Publikováno v: TP74. TP074 CYSTIC FIBROSIS AND PRIMARY CILIARY DYSKINESIA.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::100068c47ce62438395326ce76449328
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3375

Ciclosporin Aggravates Tissue Damage in Ischemia Reperfusion-Induced Acute Pancreatitis

Autor: Jens Werner, Thilo Hackert, Stefan Fritz, Ernst Klar, D. Pfeil, Werner Hartwig, Martha-Maria Gebhard

Publikováno v: Pancreas. 32:145-151

OBJECTIVES Ischemia reperfusion (I/R)-associated early graft pancreatitis is a major complication after pancreas transplantation. The influence of immunosuppressants on graft pancreatitis remains unclear. The aim of this study was to evaluate ciclosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fef5cefd5f2b67acd1b890d7c5e573d
https://doi.org/10.1097/01.mpa.0000194610.62723.18

Activation of Mitogen-activated Protein Kinases p42/44, p38, and Stress-activated Protein Kinases in Myelo-monocytic Cells byTreponema Lipoteichoic Acid

Autor: Ulrich Zähringer, D. Pfeil, Ulf B. Göbel, Bastian Opitz, Johannes Amberger, Kathrin S. Michelsen, Nicolas W.J. Schröder, Ralf R. Schumann

Publikováno v: Journal of Biological Chemistry. 276:9713-9719

We have shown previously that phenol/water extracts derived from two novel Treponema species, Treponema maltophilum, and Treponema brennaborense, resembling lipoteichoic acid (LTA), induce cytokines in mononuclear cells. This response was lipopolysac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ff30294c47324ee5e4f3b6ac4eea41
https://doi.org/10.1074/jbc.m008954200

Effects of site-directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS)-binding protein on binding and transfer of LPS and subsequent immune cell activation

Autor: N Lamping, A Hoess, B Yu, T C Park, C J Kirschning, D Pfeil, D Reuter, S D Wright, F Herrmann, R R Schumann

Publikováno v: The Journal of Immunology. 157:4648-4656

LPS-binding protein (LBP) is a 60-kDa acute phase glycoprotein capable of binding the LPS of Gram-negative bacteria and facilitating its diffusion. This process is thought to be of potential importance in inflammatory reactions and pathogenic states

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a33bed413f2e95c4446ee4843e5f68a
https://doi.org/10.4049/jimmunol.157.10.4648

Bedeutung der Thrombozyten für Mikrozirkulation und Gewebeschaden bei der experimentellen akuten Pankreatitis

Autor: D. Pfeil, T. Hackert, Werner Uhl, W Hartwig, John S. Werner, Gebhard Mm, M.W. Büchler

Publikováno v: 121. Kongress der Deutschen Gesellschaft für Chirurgie; 20040427-20040430; Berlin; DOC04dgch0944 /20041007/
Deutsche Gesellschaft für Chirurgie ISBN: 9783540200277

Background: Acute pancreatitis (AP) is characterized by a disturbance of pancreatic microcirculation, leading to ischemia and consequently necrosis of pancreatic tissue. Leukocyte activation and erythrocyte flow patterns have been well investigated d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37bad52d2a471124f64d926aeec6947
http://www.egms.de/en/meetings/dgch2004/04dgch561.shtml