Zobrazeno 1 - 10
of 21
pro vyhledávání: '"D Peter O'Leary"'
Autor:
D Peter O'Leary, Lavinia Bhatt, John F Woolley, David R Gough, Jiang H Wang, Thomas G Cotter, H Paul Redmond
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e44176 (2012)
Surgery induced inflammation is a potent promoter of tumour recurrence and metastasis in colorectal cancer. The recently discovered family of Nox enzymes represent a major source of endogenous reactive oxygen species (ROS) and are now heavily implica
Externí odkaz:
https://doaj.org/article/9a69a4d32b7b499c8cd8e8bc1ce3e18c
Autor:
Huiting Zhou, Andrew P. Coveney, Ming Wu, Jie Huang, Siobhan Blankson, He Zhao, D. Peter O'Leary, Zhenjiang Bai, Yiping Li, H. Paul Redmond, Jiang Huai Wang, Jian Wang
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The detection of microbial pathogens relies on the recognition of highly conserved microbial structures by the membrane sensor Toll-like receptors (TLRs) and cytosolic sensor NOD-like receptors (NLRs). Upon detection, these sensors trigger innate imm
Externí odkaz:
https://doaj.org/article/e912dba1da5d4e21bf02c492fa845a11
Autor:
D. Peter O’Leary, Jiang Huai Wang, H. Paul Redmond, Rolf W. Pfirrmann, Mark Corrigan, M. Jinih
Publikováno v:
Anticancer Research. 41:2247-2256
Background/aim Adjuvant therapeutic options are limited for triple negative breast cancer (TNBC). Thus, we evaluated the cytotoxic effects of the newly synthesized antineoplastic agent 1,4,5-Oxathiazinane-4,4-dioxide (OTD) on TNBC cells as a potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d3c665910a3301ffb1c6657086295f
https://doi.org/10.21873/anticanres.15001
https://doi.org/10.21873/anticanres.15001
Autor:
Arnold D.K. Hill, Ruth Dunne, Will Robb, Siun M Walsh, Sorcha O’Grady, Martina M. Morrin, Jan Sørensen, Niamh McCawley, Aisling Hegarty, John P. Burke, Chwanrow Baban, Jarlath C. Bolger, Colm Power, Jack Alderson, D. Peter O’Leary, Deborah A. McNamara, Hilary Humphreys, Michael J. Lee, Mark Sheehan, Aoife M. Lee
Publikováno v:
Annals of Surgery. 274:240-247
OBJECTIVE Evaluate the efficacy and quality of life associated with conservative treatment of acute uncomplicated appendicitis. SUMMARY BACKGROUND DATA Conservative management with antibiotics only has emerged as a potential treatment option for acut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7694048caf8f2de447728a7351ff8163
https://doi.org/10.1097/sla.0000000000004785
https://doi.org/10.1097/sla.0000000000004785
Autor:
Jie Huang, Michael Ita, Huiting Zhou, He Zhao, Fara Hassan, Zhenjiang Bai, D. Peter O’Leary, Yiping Li, H. Paul Redmond, Jiang Huai Wang, Jian Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Sepsis, septic shock, and their sequelae are the leading causes of death in intensive care units, with limited therapeutic options. Disease resistance and tolerance are two evolutionarily conserved yet distinct defense strategies that protect the hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1126eeab9efa7cb30d5d130869762da7
https://doi.org/10.1073/pnas.2121244119
https://doi.org/10.1073/pnas.2121244119
Autor:
D Peter, O'Leary, Arnold, Hill
Publikováno v:
Annals of Surgery. 276:e1119-e1120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef72a70d7beec453c6aaa2c4a7c9bf2f
https://doi.org/10.1097/sla.0000000000005368
https://doi.org/10.1097/sla.0000000000005368
Publikováno v:
European Journal of Surgical Oncology. 47:e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b82007fc1eb45e024d7ab433bef5fd0
https://doi.org/10.1016/j.ejso.2020.11.029
https://doi.org/10.1016/j.ejso.2020.11.029
Autor:
D Peter O'leary, J. Calvin Coffey
Publikováno v:
Expert Review of Gastroenterology & Hepatology. 11:703-705
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620599be7b176a809bb25b3cde725b76
https://doi.org/10.1080/17474124.2017.1329010
https://doi.org/10.1080/17474124.2017.1329010
Autor:
E. O'Connell, N.M. Foley, H. Paul Redmond, Rolf W. Pfirrmann, D. Peter O’Leary, Jiang Huai Wang, Peter Neary, M. Jinih
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
BMC Cancer
BMC Cancer
Peri-operative inflammation has been extensively highlighted in cancer patients as detrimental. Treatment strategies to improve survival for cancer patients through targeting peri-operative inflammation have yet to be devised. We conducted a multi-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2a6d581bef1242a2c4b8b2a8394530
https://doi.org/10.1186/s12885-018-4641-x
https://doi.org/10.1186/s12885-018-4641-x
Publikováno v:
Melanoma Research. 25:1-8
Treatment strategies for metastatic melanoma have changed markedly in recent times due to the advent of targeted systemic therapies. In addition to these developments, surgery remains a useful adjunct that can confer survival benefits in selected pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0b6f4dcb5991c405b3baacd80636c8
https://doi.org/10.1097/cmr.0000000000000128
https://doi.org/10.1097/cmr.0000000000000128