Zobrazeno 1 - 10
of 810
pro vyhledávání: '"D Pavord"'
Autor:
Imran Howell, Daniel J. Bratton, Gareth Hynes, Steven W. Yancey, Liam G. Heaney, Ian D. Pavord, Rahul Shrimanker
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/3b8c5c21aa064df2a187442b962f2729
Autor:
Imran Howell, Mahdi Mahdi, Mona Bafadhel, Timothy S C Hinks, Sanjay Ramakrishnan, James Melhorn, Maisha Jabeen, Ian D Pavord
Publikováno v:
JMIR Research Protocols, Vol 12, p e46741 (2023)
BackgroundAsthma attacks are a common and important problem. Someone experiences an asthma attack in the United Kingdom every 10 seconds. Asthma attacks cause coughing, wheezing, breathlessness, and chest tightness and are highly stressful for patien
Externí odkaz:
https://doaj.org/article/5743537235b64bc896ae9c835ee40c01
Autor:
Mary A. Brown, Sophie B. Morgan, Gillian E. Donachie, Katie L. Horton, Ian D. Pavord, Carolina V. Arancibia-Cárcamo, Timothy S. C. Hinks
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Type-2 low asthma affects 30-50% of people with severe asthma and includes a phenotype characterized by sputum neutrophilia and resistance to corticosteroids. Airways inflammation in type-2 low asthma or COPD is potentially driven by persistent bacte
Externí odkaz:
https://doaj.org/article/bd5171c66c424a6c9377defadc7e44cf
Autor:
Jian Luo, Yi-Ling Chen, Wentao Chen, David A. Duncan, Alexander Mentzer, Julian C. Knight, Graham Ogg, Paul Klenerman, Ian D. Pavord, Luzheng Xue
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 17, Iss 1, Pp 1-12 (2021)
Abstract Background A significant portion of COVID-19 sufferers have asthma. The impacts of asthma on COVID-19 progression are still unclear but a modifying effect is plausible as respiratory viruses are acknowledged to be an important trigger for as
Externí odkaz:
https://doaj.org/article/4b58fd785efe404680c16041aaa2a841
Autor:
Ian D. Pavord, Roland Buhl, Monica Kraft, Charlene M. Prazma, Robert G. Price, Peter H. Howarth, Steven W. Yancey
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/76317a21f29a45408905b93037f416d6
Autor:
Maisha F. Jabeen, Nicholas D. Sanderson, Dona Foster, Derrick W. Crook, Jennifer L. Cane, Catherine Borg, Clare Connolly, Samantha Thulborn, Ian D. Pavord, Paul Klenerman, Teresa L. Street, Timothy S. C. Hinks
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Previous metagenomic studies in asthma have been limited by inadequate sequencing depth for species-level bacterial identification and by heterogeneity in clinical phenotyping. We hypothesize that chronic bacterial airways infection is a key
Externí odkaz:
https://doaj.org/article/0464dc30468d4d348813c307c41c71f2
Autor:
Andrew Bush, Ian D. Pavord
Publikováno v:
Breathe, Vol 18, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/18f59738cc024457b10bf498ad26b08c
Autor:
Timothy S. C. Hinks, Vicki S. Barber, Joanna Black, Susan J. Dutton, Maisha Jabeen, James Melhorn, Najib M Rahman, Duncan Richards, Daniel Lasserson, Ian D. Pavord, Mona Bafadhel
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Azithromycin is an orally active synthetic macrolide antibiotic with a wide range of anti-bacterial, anti-inflammatory and antiviral properties. It is a safe, inexpensive, generic licenced drug available worldwide and manufactured
Externí odkaz:
https://doaj.org/article/19d00ac2299846e6a46eeac19fd7e892
Autor:
Richard Beasley, James Harper, Grace Bird, Harriette Dunphy, Alex Semprini, Ian D. Pavord, Alberto Papi, Mark Weatherall
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background and objective The dose-response relationship of inhaled corticosteroid (ICS)/fast-onset long acting beta agonist (LABA) reliever therapy has not been formally addressed. The objective of this retrospective analysis is to ascertain
Externí odkaz:
https://doaj.org/article/127ad60dad3d450ba34cda8ccaf3d542
Autor:
Andrew Bush, Ian D. Pavord
Publikováno v:
Breathe, Vol 17, Iss 3 (2021)
Airway diseases were initially described by nonspecific patterns of symptoms, for example “dry and wheezy” and “wet and crackly”. The model airway disease is cystic fibrosis, which has progressed from nonspecific reactive treatments such as a
Externí odkaz:
https://doaj.org/article/33deba64f26647cc9ad2ffcd05c36cb2