Zobrazeno 1 - 10
of 133
pro vyhledávání: '"D Paraiso"'
Autor:
Shreyasi Mukherjee, Praneet Chaturvedi, Scott A Rankin, Margaret B Fish, Marcin Wlizla, Kitt D Paraiso, Melissa MacDonald, Xiaoting Chen, Matthew T Weirauch, Ira L Blitz, Ken WY Cho, Aaron M Zorn
Publikováno v:
eLife, Vol 9 (2020)
Lineage specification is governed by gene regulatory networks (GRNs) that integrate the activity of signaling effectors and transcription factors (TFs) on enhancers. Sox17 is a key transcriptional regulator of definitive endoderm development, and yet
Externí odkaz:
https://doaj.org/article/099fd6889c844b1e940c404adbcee5ef
Autor:
Boni A. Afouda, Yukio Nakamura, Sophie Shaw, Rebekah M. Charney, Kitt D. Paraiso, Ira L. Blitz, Ken W.Y. Cho, Stefan Hoppler
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101314- (2020)
Summary: Although Wnt/β-catenin signaling is generally conserved and well understood, the regulatory mechanisms controlling context-specific direct Wnt target gene expression in development and disease are still unclear. The onset of zygotic gene tr
Externí odkaz:
https://doaj.org/article/db113fb346e24e129dd2a39f7b2d443d
Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation
Autor:
Kitt D. Paraiso, Ira L. Blitz, Masani Coley, Jessica Cheung, Norihiro Sudou, Masanori Taira, Ken W.Y. Cho
Publikováno v:
Cell Reports, Vol 27, Iss 10, Pp 2962-2977.e5 (2019)
Summary: Elucidation of the sequence of events underlying the dynamic interaction between transcription factors and chromatin states is essential. Maternal transcription factors function at the top of the regulatory hierarchy to specify the primary g
Externí odkaz:
https://doaj.org/article/8d71e61402744265b81158bf2a437b06
Autor:
Arianne Diane A. Aniñon, Richard Simon R. Binos, Karen Mae M. Brizuela, Willison John C. de Luna, Regine Philline S. del Rosario, Jesus John C. Dimalala, Timothy Joseph P. Dueñas, Isaac Ireneo B. Linatoc, Juan Paolo D. Recto, Melanie V. Salinas, West Kristian D. Paraiso
Publikováno v:
Science Diliman, Vol 26, Iss 1, Pp 41-52 (2014)
In the quality control of pharmaceutical products, it is of utmost importance that validated analytical methods are used to ensure the credibility of the results generated. At the time of the study, official monographs from the United States Pharmaco
Externí odkaz:
https://doaj.org/article/a49a254087f142b490b75c7fceb5caa5
Autor:
Ira L. Blitz, Rebekah M. Charney, Margaret B. Fish, Camden Jansen, Kitt D. Paraiso, Jeff Jiajing Zhou, Aaron M. Zorn, Yuuri Yasuoka, Gert Jan C. Veenstra, Ali Mortazavi, M. Wlizla, Jin Sun Cho, Ann Rose Bright, Ken W.Y. Cho, Norihiro Sudou, Masanori Taira
Publikováno v:
Cell reports, vol 38, iss 7
Cell Reports, 38, 7, pp. 1-23
Cell Reports, 38, 1-23
Cell Reports, 38, 7, pp. 1-23
Cell Reports, 38, 1-23
SummaryMesendodermal specification is one of the earliest events in embryogenesis, where cells first acquire distinct identities. Cell differentiation is a highly regulated process that involves the function of numerous transcription factors (TFs) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c724bc6ffdb1da3af7e947d8305c88e
https://escholarship.org/uc/item/1ms272nq
https://escholarship.org/uc/item/1ms272nq
Autor:
Kitt D. Paraiso, Ping H. Wang, Zhuyuan Fang, Qin Yang, Ira L. Blitz, Qiushi Sun, Haibo Cheng, Hank Chen, Marcus Seldin, Fang Yuan, Lingyi Tang, Yuan Fang, Xiaorong Wang, Zhengxia Liu, Ken W.Y. Cho, Xiang Lu, Xiaolong Ye, Kang Du, Clinton Yu, Yumay Chen, Yang Cao, Lan Huang
Publikováno v:
JCI Insight
JCI insight, vol 6, iss 17
JCI insight, vol 6, iss 17
Mitochondrial biogenesis and function are controlled by anterograde regulatory pathways involving more than 1000 nuclear-encoded proteins. Transcriptional networks controlling the nuclear-encoded mitochondrial genes remain to be fully elucidated. Her
Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation
Autor:
Ira L. Blitz, Masani Coley, Ken W.Y. Cho, Kitt D. Paraiso, Jessica Cheung, Norihiro Sudou, Masanori Taira
Publikováno v:
Cell Reports, Vol 27, Iss 10, Pp 2962-2977.e5 (2019)
Cell reports
Cell reports
SUMMARY Elucidation of the sequence of events underlying the dynamic interaction between transcription factors and chromatin states is essential. Maternal transcription factors function at the top of the regulatory hierarchy to specify the primary ge
One of the first steps in cellular differentiation of vertebrate embryos is the formation of the three germ layers. Maternal pioneer transcription factors (TFs) bind to the regulatory regions of the embryonic genome prior to zygotic genome activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64adc2905cac0679b052c948189d41f5
https://doi.org/10.1101/2021.04.14.439777
https://doi.org/10.1101/2021.04.14.439777
Autor:
Laura Herrero, Jordi Garcia, Hiroaki Kinoh, Shigeto Fukushima, Rosalía Rodríguez-Rodríguez, Núria Casals, Yuki Mochida, Jesús Garcia-Chica, Kazunori Kataoka, Sabina Quader, Dolors Serra, West Kristian D. Paraiso, Sebastián Zagmutt, Xavier Ariza
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Carnitine palmitoyltransferase 1A (CPT1A) is a central player in lipid metabolism, catalyzing the first step to fatty acid oxidation (FAO). Inhibiting CPT1A, especially in the brain, can have several pharmacological benefits, such as in treating obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97531899c73ccc312bcf24533ca2505
http://hdl.handle.net/2445/180168
http://hdl.handle.net/2445/180168
Autor:
Sabina Quader, West Kristian D. Paraiso, Xueying Liu, Kazunori Kataoka, Hiraoki Kinoh, Horacio Cabral
Publikováno v:
The 2nd International Online-Conference on Nanomaterials.