Zobrazeno 1 - 6
of 6
pro vyhledávání: '"D P Ménard"'
Publikováno v:
The Journal of Neuroscience. 16:2342-2351
Tolerance to morphine analgesia is believed to result from a neuronal adaptation produced by continuous drug administration, although the precise mechanisms involved have yet to be established. Recently, we reported selective alterations in rat spina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc5c327eda7044872f5561933ef92b9
https://doi.org/10.1523/jneurosci.16-07-02342.1996
https://doi.org/10.1523/jneurosci.16-07-02342.1996
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 73:1089-1095
Calcitonin gene related peptide (CGRP), one of the most abundant peptides in the spinal cord, is localized in primary afferents and released following nociceptive stimuli. Its colocalization and corelease with substance P, a well-known nociceptive ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4c42dd373eaecf9b04a33374594855
https://doi.org/10.1139/y95-156
https://doi.org/10.1139/y95-156
Publikováno v:
British journal of pharmacology. 129(8)
Opioid receptors in the brain activate descending pain pathways to inhibit the nociceptive response to acute noxious stimuli. The aim of the present study was to clarify the role of supraspinal opioid receptors in modulating the nociceptive response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52af06ca19e057f47b29e318479984ee
https://pubmed.ncbi.nlm.nih.gov/10780972
https://pubmed.ncbi.nlm.nih.gov/10780972
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(2)
Tolerance to the spinal antinociceptive effects of morphine develops rapidly after its chronic administration. The mechanism involved in this phenomenon is unclear, but it is unlikely due to a direct regulation of spinal opioid peptides and their rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d44c49c02134c09527de17d3d0f46c6c
https://pubmed.ncbi.nlm.nih.gov/7752094
https://pubmed.ncbi.nlm.nih.gov/7752094
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 270(2)
Amylin is a recently isolated peptide from amyloid plaques in noninsulin-dependent diabetic patients and showed high sequence homology with calcitonin gene-related peptide. We investigated the distribution and the binding profile of [125I]Bolton Hunt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e72d3f0ab7a6b87f8f1a81152998015
https://pubmed.ncbi.nlm.nih.gov/8071870
https://pubmed.ncbi.nlm.nih.gov/8071870
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 269(2)
The calcitonin gene-related peptide (CGRP) C-terminal fragment human CGRP8-37 acts as a potent antagonist of various in vitro and in vivo effects of CGRP. Its iodinated counterpart, [125I-Tyr] hCGRP8-37, binds with high affinity (KD values between 7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03afa6f5f3e774d212849c7c1a397687
https://pubmed.ncbi.nlm.nih.gov/8182554
https://pubmed.ncbi.nlm.nih.gov/8182554