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Induction of neuronal death by alpha-synuclein

Autor: A R, Saha, N N, Ninkina, D P, Hanger, B H, Anderton, A M, Davies, V L, Buchman

Publikováno v: The European journal of neuroscience. 12(8)

The molecular and cellular mechanisms underlying neuronal loss in neurodegenerative diseases are unclear. It is generally thought that aggregation of mutated, abnormally modified or abnormally folded proteins leads to the accumulation of extracellula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38bd2fb87ffbb4a7b214646be4d81990
https://pubmed.ncbi.nlm.nih.gov/10971650

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The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and beta-amyloid in primary rat cortical neuronal cultures

Autor: D R Davis, J P Brion, A M Couck, J M Gallo, D P Hanger, K Ladhani, C Lewis, C C J Miller, T Rupniak, C Smith, B H Anderton

Publikováno v: Scopus-Elsevier

The effects of the excitatory amino acid glutamate, the microtubule destabilizing agent colchicine, and beta 25-35-amyloid peptide on the phosphorylation state of tau were studied in rat cortical neurons in primary culture. Using immunocytochemistry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cc1f799a60f87fb9b339f1820704c1
https://pubmed.ncbi.nlm.nih.gov/7639714

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