Zobrazeno 1 - 10
of 45
pro vyhledávání: '"D P Benziger"'
Publikováno v:
Clinical nephrology. 75(1)
The purpose of this study was to characterize the pharmacokinetics and tolerability of daptomycin in subjects undergoing hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD).16 noninfected adults on stable dialysis regimens were enro
Autor:
D E, Katz, K C, Lindfield, J N, Steenbergen, D P, Benziger, K J, Blackerby, A G, Knapp, W J, Martone
Publikováno v:
International journal of clinical practice. 62(9)
Methicillin-susceptible and -resistant (MRSA) Staphylococcus aureus are significant causes of complicated skin and skin structure infections (cSSSI). The bactericidal antibiotic daptomycin is approved for gram-positive cSSSI at 4 mg/kg/day for 7-14 d
Autor:
Paul J. Fielder, Andrew R. Hoffman, Le Dao, David M. Cook, J. D. Reimann, D. P. Benziger, Kathleen Ford, Beverly M. K. Biller, A. Illeperuma, Kenneth M. Attie, Mary Lee Vance, Lawrence S. Phillips, Sandra L. Blethen
Publikováno v:
The Journal of clinical endocrinology and metabolism. 87(10)
Long-term GH replacement therapy is indicated for children with growth failure due to GH deficiency (GHD). We evaluated the feasibility of administering a long-acting GH preparation [Nutropin Depot (somatropin, rDNA origin) for injectable suspension]
Autor:
D P Benziger, J A Johnson
Publikováno v:
Antimicrobial Agents and Chemotherapy. 27:774-781
Sprague-Dawley rats received [14C]amifloxacin mesylate either orally or intravenously at 20 mg (base equivalent) per kg. Blood radioactivity peaked at 0.5 h after oral administration and was equivalent to 7.54 micrograms/ml for males and 6.73 microgr
Autor:
D P Benziger, J Edelson
Publikováno v:
Antimicrobial Agents and Chemotherapy. 22:475-481
[14C]arildone was administered both topically and intravaginally to mice 5 times a day for 7 days to simulate conditions of clinical usage. Urinary and fecal excretion of radioactivity indicated that arildone was extensively absorbed by both routes o
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 258(1)
The disposition of quinfamide 1-(dichloroacetyl)-6-(2-furoyloxy)-1, 2, 3, 4-tetrahydroquinoline, an enteric anti-amoebic agent, was studied in the rat. A peak blood level equivalent to 2.3 micrograms/ml of quinfamide was observed at 7 hr following a
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 5(3)
Radioactivity from orally administered single doses of cyclindole-14C was excreted primarily in the urine of the rat (99%/48 hr), monkey (80%/120 hr), and dog (70%/144 hr). Approximately 38-58% of a daily dose of cyclindole was recovered from 24-hr h
Publikováno v:
Clinical pharmacology and therapeutics. 40(6)
Ten healthy male subjects were phenotyped with isoniazid for their acetylator status and then received intravenous amrinone at a dose of 75 mg during a period of 10 minutes. Blood samples were drawn at specified times during a 24-hour period after do
Publikováno v:
The Journal of infectious diseases. 154(4)
liver, serum (ng/ml), and muscle, respectively at 0.5-1.0 hr after medication. The picornaviruses, a group of small, single-stranded RNA viruses, are the causative agents of several disease states. Among the picornaviridae are two groups that cause d
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 9(6)
Peak levels of radioactivity in blood occurred 1.0 hr after oral administration of 3H-sulfinalol hydrochloride to rats, dogs, and monkeys. The plasma decay curve for intact sulfinalol in the dog was biphasic, with apparent first-order half-lives of 0