Zobrazeno 1 - 10
of 36
pro vyhledávání: '"D P, Witte"'
Autor:
Frederieke A. J. Gigase, Mara Graziani, Juliana Castro, Corina Lesseur, Anna-Sophie Rommel, Tammy Flores, M. Mercedes Perez-Rodriguez, Siobhan Dolan, Joanne Stone, Teresa Janevic, Whitney Lieb, Veerle Bergink, Lot D. de Witte
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Disturbances in T-cells, specifically the Th17/Treg balance, have been implicated in adverse pregnancy outcomes. We investigated these two T-cell populations following pre-pregnancy and pregnancy SARS-CoV-2 infection and COVID-19 vaccination in 351 p
Externí odkaz:
https://doaj.org/article/1aab4c10d6314097939a6c7b5e4ef6c8
Autor:
Anna Suleri, Charlotte Cecil, Anna-Sophie Rommel, Manon Hillegers, Tonya White, Lot D. de Witte, Ryan L. Muetzel, Veerle Bergink
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract There is convincing evidence from rodent studies suggesting that prenatal infections affect the offspring’s brain, but evidence in humans is limited. Here, we assessed the occurrence of common infections during each trimester of pregnancy
Externí odkaz:
https://doaj.org/article/a835beb148f64dfbb48020ccbd8b79fb
Autor:
Jihan K. Zaki, Santiago G. Lago, Nitin Rustogi, Shiral S. Gangadin, Jiri Benacek, Geertje F. van Rees, Frieder Haenisch, Jantine A. Broek, Paula Suarez-Pinilla, Tillmann Ruland, Bonnie Auyeung, Olya Mikova, Nikolett Kabacs, Volker Arolt, Simon Baron-Cohen, Benedicto Crespo-Facorro, Hemmo A. Drexhage, Lot D. de Witte, René S. Kahn, Iris E. Sommer, Sabine Bahn, Jakub Tomasik
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract A significant proportion of the personal and economic burden of schizophrenia can be attributed to the late diagnosis or misdiagnosis of the disorder. A novel, objective diagnostic approaches could facilitate the early detection and treatmen
Externí odkaz:
https://doaj.org/article/c80de718941446dfb6c9665174400e1e
Publikováno v:
Journal of Affective Disorders Reports, Vol 11, Iss , Pp 100465- (2023)
There is special interest in antidepressants as potential repurposing drugs for neurodegenerative disorders (ND). Microglia activation is implicated to play a causal role in the pathogenesis of ND. Furthermore, preclinical studies showed profound imp
Externí odkaz:
https://doaj.org/article/baf6b7c96ac143069b382a4b7450764c
Autor:
Tatiana Oviedo-Salcedo, Elias Wagner, Mattia Campana, Anna Gagsteiger, Wolfgang Strube, Peter Eichhorn, Marie-Luise Louiset, Jurjen Luykx, Lot D. de Witte, René S. Kahn, Michael E. Benros, Peter Falkai, Alkomiet Hasan
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Multiple lines of evidence indicate that immunological and inflammatory alterations contribute at least in a subgroup to the pathophysiology of schizophrenia. In this retrospective chart review, we investigated whether clinical factors contr
Externí odkaz:
https://doaj.org/article/a020f0473bed4881985f1532bdddf358
Autor:
Mareike Aichholzer, Shiral S. Gangadin, Iris E.C. Sommer, Annemarie Wijkhuis, Lot D. de Witte, René S. Kahn, Sabine Bahn, Hemmo A. Drexhage, Carmen Schiweck
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100551- (2022)
Immune dysregulation has been reported in schizophrenia spectrum disorders (SSD). In the past decade, several trials using anti-inflammatory agents for treatment of SSD have been completed, with so far limited success. One such anti-inflammatory agen
Externí odkaz:
https://doaj.org/article/2cbecf90a5854499bfb8804c119463f7
Akademický článek
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Autor:
Yujie He, Lot D. de Witte, Lotte C. Houtepen, Danny M. Nispeling, Zhida Xu, Qiong Yu, Yaqin Yu, Elly M. Hol, René S. Kahn, Marco P. Boks
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-8 (2019)
Abstract Background DNA methylation has recently been identified as a mediator between in utero famine exposure and a range of metabolic and psychiatric traits. However, genome-wide analyses are scarce and cross-sectional analyses are hampered by man
Externí odkaz:
https://doaj.org/article/6b2a6789cf4a4c20881b2cb639dd7079
Autor:
Amber Berdenis van Berlekom, Raphael Kübler, Jeske W. Hoogeboom, Daniëlle Vonk, Jacqueline A. Sluijs, R. Jeroen Pasterkamp, Jinte Middeldorp, Aletta D. Kraneveld, Johan Garssen, René S. Kahn, Elly M. Hol, Lot D. de Witte, Marco P. Boks
Publikováno v:
Nutrients, Vol 14, Iss 10, p 2175 (2022)
Evidence of the impact of nutrition on human brain development is compelling. Previous in vitro and in vivo results show that three specific amino acids, histidine, lysine, and threonine, synergistically inhibit mTOR activity and behavior. Therefore,
Externí odkaz:
https://doaj.org/article/c1b685c455274e278387fcd4f6b37a9f
Autor:
Stephanie B. H. Gumbs, Amber Berdenis van Berlekom, Raphael Kübler, Pauline J. Schipper, Lavina Gharu, Marco P. Boks, Paul R. Ormel, Annemarie M. J. Wensing, Lot D. de Witte, Monique Nijhuis
Publikováno v:
Viruses, Vol 14, Iss 4, p 829 (2022)
The achievement of an HIV cure is dependent on the eradication or permanent silencing of HIV-latent viral reservoirs, including the understudied central nervous system (CNS) reservoir. This requires a deep understanding of the molecular mechanisms of
Externí odkaz:
https://doaj.org/article/2321f20662244c68ae92d104af4ad726