Zobrazeno 1 - 10
of 31
pro vyhledávání: '"D P, Via"'
Autor:
A N Orekhov, V V Tertov, I A Sobenin, V N Smirnov, D P Via, J Guevara, Jr, AM Gotto, Jr, JD Morrisett
Publikováno v:
Journal of Lipid Research, Vol 33, Iss 6, Pp 805-817 (1992)
Low density lipoproteins (LDL) isolated from the plasma of patients with angiographically demonstrable coronary heart disease (CHD) induced accumulation of triglycerides, free cholesterol, and cholesteryl esters in cultured macrophages, smooth muscle
Externí odkaz:
https://doaj.org/article/f45d607a54c04980a06aebb97e01490f
Low density lipoproteins reconstituted with steroids containing the nitrobenzoxadiazole fluorophore.
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 4, Pp 687-696 (1981)
A new cholesterol analog, N-(7-nitrobenz-2-oxa-1,3-diazole)-23,24-dinor-5-cholen-22-amine-3 beta-ol, with fluorescent properties similar to those of fluorescein, has been synthesized. The fluorescence lifetimes, quantum yields, and wavelength maxima
Externí odkaz:
https://doaj.org/article/25b9c287d24e43f1804253425df6f322
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 4, Pp 570-576 (1982)
A method has been devised for the preparation of stable lipid microemulsions containing cholesterol, cholesteryl ester, phosphatidylcholine, and trioleoylglycerol in the relative molar ratios found in low density lipoproteins. Gel permeation chromato
Externí odkaz:
https://doaj.org/article/48eec15363794296b412825a76b1aa2c
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 10, Pp 1515-1524 (1989)
Human monocytic cell line THP-1 incubated with as little as 10 ng/ml of phorbol myristate acetate bound and metabolized 1-2 micrograms of Ac-LDL over a 5-h period. In the absence of phorbol treatment, no specific metabolism of Ac-LDL occurred. Optima
Externí odkaz:
https://doaj.org/article/6f590f87d25b413c924be3c87019c2f3
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 7, Pp 1097-1111 (1989)
The separation of the acetate derivatives of a number of oxygenated sterols was achieved by medium pressure liquid chromatography on silica gel columns and by normal and reversed phase high performance liquid chromatography. We have explored the appl
Externí odkaz:
https://doaj.org/article/6ac797720e194cf0a101d1335dfb16cc
Publikováno v:
Journal of Lipid Research, Vol 27, Iss 4, Pp 412-420 (1988)
Very low density lipoproteins Sf 100-400 (VLDL1) from hypertriglyceridemic (HTG) subjects and chylomicrons cause receptor-mediated lipid engorgement in unstimulated macrophages in vitro via the beta-VLDL receptor pathway. We now report that the murin
Externí odkaz:
https://doaj.org/article/f32b232ec9cb4b2f9562221f91bbc7aa
Publikováno v:
Journal of Clinical Investigation. 96:260-272
Hepatic scavenger receptors (SR) may play a protective role by clearing modified lipoproteins before they target the artery wall. To gain insight into this hypothesized function, transgenic mice expressing hepatic bovine SR (TgSR) were created and st
Publikováno v:
Biochemical Journal. 265:689-698
The binding characteristics of reduced hepatic membrane proteins for acetylated low-density lipoprotein (acetyl-LDL) and maleylated bovine serum albumin (Mal-BSA) have been examined. Two receptor activities were extracted from hepatic membranes in th
Autor:
M P, Mims, A T, Darnule, R W, Tovar, H J, Pownall, D A, Sparrow, J T, Sparrow, D P, Via, L C, Smith
Publikováno v:
The Journal of biological chemistry. 269(32)
ApoE is a 34-kDa apoprotein that mediates lipoprotein binding to the low density lipoprotein (LDL) receptor and to the LDL receptor-related protein. Receptor binding is mediated by a highly basic, alpha-helical sequence of approximately 15 amino acid
Publikováno v:
The Biochemical journal. 281
Reduced hepatic membrane receptors for acetylated low-density lipoprotein (acetyl-LDL) and maleylated BSA (Mal-BSA) with apparent molecular masses of 35 kDa, 85 kDa and 15 kDa have been extracted from rat liver and separated by affinity chromatograph