LAB-OMICS AND PROGNOSTIC MARKERS

Autor: R. L. Jensen, S. Abraham, N. Hu, J.-L. Boulay, S. Leu, S. Frank, E. Vassella, I. Vajtai, S. von Felten, E. Taylor, M. Schulz, G. Hutter, M. Sailer, J. Hench, L. Mariani, H. F. van Thuijl, I. Scheinin, D. F. van Essen, J. J. Heimans, P. Wesseling, B. Ylstra, J. C. Reijneveld, A. R. Borges, P. L. Larrubia, J. M. B. Marques, S. G. Cerdan, P. Brastianos, P. Horowitz, S. Santagata, R. T. Jones, A. McKenna, G. Getz, K. Ligon, E. Palescandolo, P. Van Hummelen, A. Stemmer-Rachamimov, D. Louis, W. C. Hahn, I. Dunn, R. Beroukhim, X. Guan, J. Vengoechea, S. Zheng, A. Sloan, Y. Chen, D. Brat, B. P. O'Neill, M. Cohen, K. Aldape, S. Rosenfeld, H. Noushmehr, R. G. Verhaak, J. Barnholtz-Sloan, E. M. Bahassi, Y.-Q. Li, E. Cross, W. Li, J. Vijg, C. McPherson, R. Warnick, P. Stambrook, O. Rixe, L. Manterola, S. Tejada-Solis, R. Diez-Valle, M. Gonzalez, P. Jauregui, N. Sampron, C. Barrena, I. Ruiz, J. Gallego, J.-Y. Delattre, A. L. de Munain, M. M. Mlonso, K. Saito, A. Mukasa, G. Nagae, K. Aihara, S. Takayanagi, H. Aburatani, N. Saito, X.-T. Kong, B. D. Fu, S. Du, A. N. Hasso, M. E. Linskey, D. Bota, C. Li, Y.-S. Chen, Z.-p. Chen, C. H. Kim, J. H. Cheong, J. M. Kim, N. P. Yelon, E. Jacoby, Z. R. Cohen, J. Ishida, K. Kurozumi, T. Ichikawa, M. Onishi, K. Fujii, Y. Shimazu, I. Date, R. Narayanan, Q. H. Ho, B. S. Levin, M. L. Maeder, J. K. Joung, C. L. Nutt, D. N. Louis, J. Thorsteinsdottir, P. Fu, M. Gehrmann, G. Multhoff, J.-C. Tonn, C. Schichor, K. Thirumoorthy, N. Gordon, S. Walston, D. Patel, M. Okamoto, A. Chakravarti, K. Palanichamy, P. French, L. Erdem, L. Gravendeel, J. de Rooi, P. Eilers, A. Idbaih, W. Spliet, W. den Dunnen, J. Teepen, P. S. Smitt, J. M. Kros, T. Gorlia, M. van den Bent, D. McCarthy, R. W. Cook, K. Oelschlager, D. Maetzold, M. Hanna, W. Wick, C. Meisner, B. Hentschel, M. Platten, M. C. Sabel, S. Koeppen, R. Ketter, M. Weiler, G. Tabatabai, A. Schilling, A. von Deimling, D. Gramatzki, M. Westphal, G. Schackert, M. Loeffler, M. Simon, G. Reifenberger, M. Weller, L. Moren, M. Johansson, T. Bergenheim, H. Antti, E. P. Sulman, L. D. Goodman, K. M. Wani, F. DeMonte, K. D. Aldape, B. Krischek, I. Gugel, D. Aref, C. Marshall, S. Croul, G. Zadeh, C. L. Nilsson, E. Sulman, H. Liu, C. Wild, C. F. Lichti, M. R. Emmett, F. F. Lang, C. Conrad, A. Alentorn, Y. Marie, B. Boisselier, C. Carpetier, K. Mokhtari, K. Hoang-Xuan, L. Capelle, T. Lautenschlaeger, A. Huebner, J. B. McIntyre, T. Magliocco, M. Hamilton, J. Easaw, B. Pollo, C. Calatozzolo, R. Vuono, S. Guzzetti, M. Eoli, A. Silvani, F. Di Meco, G. Filippini, G. Finocchiaro, A. Joy, A. Ramesh, I. Smirnov, M. Reiser, W. Shapiro, G. Mills, S. Kim, B. Feuerstein, D. D. Gonda, J. Li, N. McCabe, S. Walker, N. Goffard, K. Wikstrom, E. McLean, C. Greenan, T. Delaney, M. McCarthy, F. McDyer, K. E. Keating, I. F. James, T. Harrison, P. Mullan, D. P. Harkin, B. S. Carter, R. D. Kennedy, C. C. Chen, A. S. Patel, J. E. Allen, D. T. Dicker, K. Rizzo, J. M. Sheehan, M. J. Glantz, W. S. El-Deiry, B. Salhia, J. T. Ross, J. Kiefer, C. Van Cott, R. Metpally, A. Baker, Z. Sibenaller, S. Nasser, T. Ryken, R. Ramanathan, M. E. Berens, J. Carpten, N. L. Tran, Y. Bi, S. Pal, Z. Zhang, R. Gupta, L. Macyszyn, H. Fetting, D. O'Rourke, R. V. Davuluri, A. M. Ezrin, K. Moore, W. Stummer, C. G. Hadjipanayis, D. P. Cahill, J. Beiko, D. Suki, S. Prabhu, J. Weinberg, F. Lang, R. Sawaya, G. Rao, I. McCutcheon, F. G. Barker, A. D. Trister, B. Bot, K. Fontes, C. Bridge, A. L. Baldock, J. K. Rockhill, M. M. Mrugala, R. R. Rockne, E. Huang, K. R. Swanson, H. R. Underhill, J. Zhang, M. Shi, X. Lin, A. Mikheev, R. C. Rostomily, A. C. Scheck, P. Stafford, A. Hughes, Z. Cichacz, S. W. Coons, S. A. Johnston, L. Mainwaring, J. Craig, D. Garcia, G. Bergthold, M. Burns, B. Rich, S. Ramkissoon, C. Eberhart, A. Ligon, L. Goumnerova, C. Stiles, M. Kieran, W. Hahn, K. H. Olausson, J. Correia, E. Gafni, M. Theisen, M. Hayashi, S. Haidar, C. Maire, L. A. Mainwaring, A. Norden, P. Wen, A. Kung, B. Alexander, P. Tonellato, K. L. Ligon

Publikováno v: Neuro-Oncology. 14:vi91-vi100

High-grade glioma is the most common brain tumor in adults, and the prognosis for patients diagnosed with this type of cancer is still poor. The biological behavior of the tumors is correlated to t ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eeeb63c14ad969cab023751e0b7ab83
https://doi.org/10.1093/neuonc/nos231

OC-0126: A gene expression assay to predict the risk of distant metastases in localized prostate cancer

Autor: Ciara Lyons, David Waugh, Sean O. Hynes, D. P. Harkin, Richard D. Kennedy, B. Pang, R.W. Watson, Elaine W. Kay, Stephen McQuaid, David E. Neal, Viktor Berge, Darren M. Mitchell, Malcolm David Mason, Jacqueline James, Gemma E Logan, Steven Walker, Joe M. O'Sullivan, A. Sheriff, Declan O'Rourke, Catherine Davidson, Andrena McCavigan, Hardev Pandha, Manuel Salto-Tellez, Suneil Jain, Laura A. Knight

Publikováno v: Radiotherapy and Oncology. 123:S59

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c926d1a4fb0bbb62f8f0189909e2cd58
https://doi.org/10.1016/s0167-8140(17)30569-8

Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70

Autor: Sean Bong Lee, Christoph Englert, Daniel A. Haber, R. T. Mccluskey, Shyamala Maheswaran, Jonathan F. Bean, Robert M. Ezzell, Gang Zheng, A. J. Garvin, Jenise C. Wong, James A. DeCaprio, D P Harkin

Publikováno v: Genes & Development. 12:1108-1120

The Wilms tumor suppressor WT1 encodes a zinc finger transcription factor that is expressed in glomerular podocytes during a narrow window in kidney development. By immunoprecipitation and protein microsequencing analysis, we have identified a major

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa67e14fa4ab439d814abd6a708dd7f3
https://doi.org/10.1101/gad.12.8.1108

BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy

Autor: Jennifer E. Quinn, G. K. F. Chang, Patrick G. Johnston, Richard H. Wilson, Paul B. Mullan, Jude M. Mulligan, Patricia M White, Colin R. James, D. P. Harkin, Gail E. Stewart

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 13(24)

Purpose: We investigated whether BRCA1 mRNA expression levels may represent a biomarker of survival in sporadic epithelial ovarian cancer following chemotherapy treatment. Experimental Design: The effect of loss of BRCA1 expression on chemotherapy re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e12ac2c2f73b259f5a0c897dbbe0a69
https://pubmed.ncbi.nlm.nih.gov/18094398

Role played by BRCA1 in regulating the cellular response to stress

Autor: P M, Gilmore, J E, Quinn, P B, Mullan, H N, Andrews, N, McCabe, M, Carty, R D, Kennedy, D P, Harkin

Publikováno v: Biochemical Society transactions. 31(Pt 1)

BRCA1 (breast-cancer susceptibility gene 1) is a tumour suppressor gene that is mutated in the germline of women with a genetic predisposition to breast and ovarian cancer. In this review, we examine the role played by BRCA1 in mediating the cellular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0deef4d15cb74d25c91aaf536ecacb74
https://pubmed.ncbi.nlm.nih.gov/12546697