Zobrazeno 1 - 10
of 17
pro vyhledávání: '"D P, Gearing"'
Publikováno v:
Novartis Foundation Symposia ISBN: 9780470514269
Ciba Foundation Symposium 167-Polyfunctional Cytokines: IL-6 and LIF
Ciba Foundation Symposium 167-Polyfunctional Cytokines: IL-6 and LIF
cDNA clones encoding the human leukaemia inhibitory factor (hLIF) receptor were isolated by screening a placental cDNA expression library in COS-7 cells with 125I-hLIF. The cloned LIF receptor is a member of the haemopoietin receptor family and compr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a999913bf68dbed2b95ad5ecca100bc6
https://doi.org/10.1002/9780470514269.ch15
https://doi.org/10.1002/9780470514269.ch15
Autor:
D. P. Gearing, Neal G. Copeland, Nancy A. Jenkins, K. Huebner, T. Druck, Debra J. Gilbert, Joan Overhauser
Publikováno v:
Genomics. 18:148-150
The leukemia inhibitory factor receptor (LIFR) gene was localized to human chromosome 5p12-p13 by somatic cell hybrid analysis. Interspecific backcross analysis revealed that the murine locus was on chromosome 15 in a region of homology with human ch
Autor:
S J, Szilvassy, K P, Weller, W, Lin, A K, Sharma, A S, Ho, A, Tsukamoto, R, Hoffman, K R, Leiby, D P, Gearing
Publikováno v:
Blood. 87(11)
Attempts to maintain or expand primitive hematopoietic stem cells in vitro without the concomitant loss of their differentiative and proliferative potential in vivo have largely been unsuccessful. To investigate this problem, we compared the ability
Autor:
Y, Wang, K K, Morella, J, Ripperger, C F, Lai, D P, Gearing, G H, Fey, S P, Campos, H, Baumann
Publikováno v:
Blood. 86(5)
To determine the specificity of signal transducer and activator of transcription (STAT) protein activation by box 3 motif-deficient hematopoietin receptors, expression vectors encoding the receptors for growth hormone, interleukin-3 (IL-3), and IL-4
Publikováno v:
The Journal of biological chemistry. 269(8)
Leukemia inhibitory factor (LIF) and oncostatin M (OSM) both bind to the same receptor with high affinity and thus mediate an overlapping spectrum of biological activities, the signal transduction mechanisms for which are unclear. We show that mitoge
Publikováno v:
The Journal of biological chemistry. 268(12)
Ciliary neurotrophic factor (CNTF) has been described as a neuro-active cytokine that shares functional similarities with the leukemia inhibitory factor (LIF). We demonstrate here that, like LIF, CNTF stimulates expression of acute phase plasma prote
Autor:
D P, Gearing
Publikováno v:
Advances in immunology. 53
Autor:
D P, Gearing, A G, Bruce
Publikováno v:
The New biologist. 4(1)
Oncostatin M (OSM) is a glycoprotein cytokine that was recently demonstrated to be structurally and functionally related to the leukemia inhibitory factor (LIF). We have investigated the binding of each cytokine to a variety of cellular receptors inc
Publikováno v:
Ciba Foundation symposium. 167
cDNA clones encoding the human leukaemia inhibitory factor (hLIF) receptor were isolated by screening a placental cDNA expression library in COS-7 cells with 125I-hLIF. The cloned LIF receptor is a member of the haemopoietin receptor family and compr
Publikováno v:
The Journal of biological chemistry. 265(15)
Leukemia inhibitory factor, LIF, is a glycoprotein with multiple activities in both the adult and the embryo. LIF appears to be encoded by a unique gene in both mouse and man, although the 3'-untranslated region of the mouse LIF gene gives a complex