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pro vyhledávání: '"D P, Creely"'
Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase
Autor:
Peter C. Isakson, Karen Seibert, James K. Gierse, D P Creely, Carol M. Koboldt, Scott D. Hauser, S H Rangwala
Publikováno v:
Biochemical Journal. 305:479-484
The enzyme cyclo-oxygenase catalyses the oxygenation of arachidonic acid, leading to the formation of prostaglandins. Recently two forms of cyclo-oxygenase have been described: a constitutive (COX-1) enzyme present in most cells and tissues, and an i
Publikováno v:
The Journal of endocrinology. 144(3)
The cDNA of the extracellular domain of bovine prolactin receptor (bPRLR-ECD) was cloned and expressed at high yield as an insoluble protein in Escherichia coli. This protein was solubilized, refolded and purified to >98% homogeneity yielding 80 mg o
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research. 23