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Autor:
D. Osoba
Publikováno v:
Neuro-Oncology. 2:221-228
Autor:
K. Bennett, Maureen E. Trudeau, K. James, Jean Latreille, T. Vandenberg, Kathleen I. Pritchard, Paul E. Goss, Wycliffe S. Lofters, Susan Marlin, Rudinskas L, J. Myles, A. Rodgers, B. Findlay, J. Skillings, B. Norris, D Osoba
Publikováno v:
Journal of Clinical Oncology. 18:2385-2394
PURPOSE: This phase III study was performed to determine the superiority of doxorubicin (DOX) and vinorelbine (VNB) (arm 1) versus DOX alone (arm 2) in metastatic breast cancer (MBC) for overall survival (OS), time to treatment failure (TTF), toxicit
Publikováno v:
Supportive Care in Cancer. 2:161-166
A number of prognostic factors have been reported to influence the probability of developing nausea and vomiting after cytotoxic chemotherapy. This study used data collected in four randomized anti-emetic trials conducted by the Clinical Trials Group
Autor:
D, Osoba
Publikováno v:
Canadian Medical Association journal. 80(1)
Autor:
D. Osoba
Publikováno v:
Quality of Life Research. 1:211-218
The Quality of Life Committee of the National Cancer Institute of Canada Clinical Trials Group has successfully advocated the adoption of quality of life outcomes in Canadian clinical trials in patients with cancer. It has developed a policy promotin
Publikováno v:
Clinical oncology (Royal College of Radiologists (Great Britain)). 14(4)
Publikováno v:
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 9(8)
Health-related quality of life (HRQL) outcomes evaluation is becoming an important component of clinical trials of new pharmaceuticals and medical devices. HRQL research provides patients, providers, and decision makers with important information on
Autor:
D Osoba
Publikováno v:
European journal of cancer (Oxford, England : 1990). 35(11)
The measurement of health-related quality of life (HRQL) in oncology clinical trials has come of age. Most cooperative clinical trials groups as well as individual institutions have either been measuring, or are starting to measure, HRQL. Over the pa
Autor:
D, Osoba, M, Burchmore
Publikováno v:
Seminars in oncology. 26(4 Suppl 12)
The measurement of health-related quality of life (HRQL) was an important component of clinical trials of trastuzumab (Herceptin; Genentech, San Francisco, CA) in women with progressive HER2-overexpressing metastatic breast cancer who may or may not