Zobrazeno 1 - 10
of 12
pro vyhledávání: '"D O Sobel"'
Publikováno v:
Diabetes. 47:1867-1872
The NOD mouse is a model of human IDDM, which is characterized by a cell-mediated autoimmune process resulting in spontaneous diabetes. Alpha-interferon (IFN-alpha) is thought to play a pathogenic role in this autoimmune process. We report that recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c3d5c56a013a03f65ab5622e1539f9
https://doi.org/10.2337/diabetes.47.12.1867
https://doi.org/10.2337/diabetes.47.12.1867
Publikováno v:
Diabetes. 43:518-522
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a693a192b7c05a98125e34dd4db92f5
https://doi.org/10.2337/diabetes.43.4.518
https://doi.org/10.2337/diabetes.43.4.518
Publikováno v:
Diabetologia. 43(8)
Aims/hypothesis. Cyclophosphamide has been shown to augment the diabetic process in NOD mouse and BB rat models of Type I (insulin-dependent) diabetes mellitus. Because cyclophosphamide has, however, been shown to increase immunoregulatory cell activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292031b9aec09a1761dfaee5e7f5b34f
https://pubmed.ncbi.nlm.nih.gov/10990075
https://pubmed.ncbi.nlm.nih.gov/10990075
Autor:
Douglas M. Strong, D. O. Sobel, Diane K. Wagener, John C. Jones, William I. Smith, James P. Gutai
Publikováno v:
Human Immunology. 7:35-44
Twenty-eight families of patients with congenital adrenal hyperplasia due to 21-hydroxylase (21-OH) deficiency were studied to evaluate the specific HLA linkage relationship and HLA antigen association to the 21-OH deficiency gene. Genotype assignmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ff39ffd3f5e049cd7df92f85ccfcc5
https://doi.org/10.1016/0198-8859(83)90005-8
https://doi.org/10.1016/0198-8859(83)90005-8
Autor:
Anthony H. Vagnucci, D. O. Sobel
Publikováno v:
Life sciences. 30(15)
Anterior pituitaries from normal rats were enzymatically dispersed and placed into monolayer cell culture in order to determine if and how angiotensin II (Ang II) mediates the in vitro release of ACTH and other pituitary hormones. Ang II stimulated A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ad2f410f1586361d90bda7e585dd56
https://pubmed.ncbi.nlm.nih.gov/6283287
https://pubmed.ncbi.nlm.nih.gov/6283287
Publikováno v:
Enzyme. 42(4)
Several hormones act at the cellular level to increase diacylglycerol via increased catabolism of phosphatidylinositol by phospholipase C. Diacylglycerol stimulates protein kinase C, leading to protein phosphorylation and hormone action. Since phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437179d58f3a47acea9412591c0917d7
https://pubmed.ncbi.nlm.nih.gov/2630290
https://pubmed.ncbi.nlm.nih.gov/2630290
Autor:
D O, Sobel, K M, Shakir
Publikováno v:
Diabetemetabolisme. 13(6)
The characteristics and clinical utility of a commercially prepared method for measuring glycated plasma proteins (glyc PP) by aminophenylboronic acid affinity chromatography is described. The measured glyc PPs after loading columns with 0.05 ml (5.9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee29c3d7394adff06c89df6776edcb8b
https://pubmed.ncbi.nlm.nih.gov/3329119
https://pubmed.ncbi.nlm.nih.gov/3329119
Publikováno v:
Clinical endocrinology. 20(3)
SUMMARY Lymphocyte transformation in response to a saline extract of human pituitary was used to evaluate anti-pituitary immunity in patients with idiopathic hypopituitarism. Nine normal subjects and three children with idiopathic hypopituitarism wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6dd8faa017b272beed4093bad98247
https://pubmed.ncbi.nlm.nih.gov/6723081
https://pubmed.ncbi.nlm.nih.gov/6723081
Autor:
D O Sobel, R E Johnsonbaugh
Publikováno v:
Pediatric Research. 15:1563-1563
We recently demonstrated that angiotensin II(AII)directly mediates in vitro ACTH secretion in rat pituitary cells.To investigate the structure activity relationship of the All molecule and intra-cellular events involved in All mediated ACTH release w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ce7468c9efccbe781399b31639daa45
https://doi.org/10.1203/00006450-198112000-00166
https://doi.org/10.1203/00006450-198112000-00166
Publikováno v:
Pediatric Research. 15:1541-1541
To obtain evidence of autoimmunity in children with idiopathic hypopituitarism, lymphocyte reactivity to pituitary extract in 9 normal subjects and 3 children with idiopathic hypopituitarism was determined. Lymphocyte reactivity to thyroid extract wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::681b5aa306f318fa8d80bbb30a7bfb4a
https://doi.org/10.1203/00006450-198112000-00037
https://doi.org/10.1203/00006450-198112000-00037