Zobrazeno 1 - 10
of 48
pro vyhledávání: '"D O Minchenko"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 3, Pp 65-77 (2019)
Numerous data demonstrate that key regulatory factors, enzymes and receptors including HSPA5, MEST, SLC1A3, PDGFC, and ADM represent poly-functional, endoplasmic reticulum stress-dependent proteins, which control variable metabolic pathways. The expr
Externí odkaz:
https://doaj.org/article/94fa4e3387d9413eae31b46b9609a9aa
Autor:
O. V. Halkin, D. O. Minchenko, О. O. Riabovol, V. V. Telychko, О. O. Ratushna, O. H. Minchenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 5, Pp 52-61 (2017)
We have studied the effect of glutamine deprivation on the expression of genes encoding for ubiquitin specific peptidases (USP) and ubiquitin activating enzyme E1-like protein/autophagy related 7 (GSA7/ATG7) in U87 glioma cells in relation to inhibit
Externí odkaz:
https://doaj.org/article/830e0ba4cac3403dbbc256df2ba5576d
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 5, Pp 40-51 (2017)
We have studied the effect of IRE1 signaling enzyme knockdown as well as hypoxia on the expression of genes encoding the important tumor growth related proteins (BRCA1, DEK, BCL2L1, COL6A1, TPD52, HOMER3, and GNPDA1) in U87 glioma cells. It was shown
Externí odkaz:
https://doaj.org/article/9dbe29a7d080434c80511ef8f65a67d7
Autor:
O. V. Halkin, O. O. Riabovol, D. O. Minchenko, A. Y. Kuznetsova, O. O. Ratushna, O. H. Minchenko
Publikováno v:
Biotechnologia Acta, Vol 10, Iss 4, Pp 34-43 (2017)
The aim of this research was to study the effect of glutamine deprivation on the expression of genes encoding for HTRA1/PRSS11, LONP1/PRSS15, and some cathepsins in U87 glioma cells in relation to inhibition of IRE1 (inositol requiring enzyme-1). It
Externí odkaz:
https://doaj.org/article/5d75137d03fd4c3584d2c6d9b8183146
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 2, Pp 55-69 (2017)
We have studied the effect of hypoxia on the expression of genes encoding for LONP1/PRSS15 and cathepsins in U87 glioma cells in relation to inhibition of inositol requiring enzyme-1 (IRE1). It was shown that hypoxia up-regulated the expression of CT
Externí odkaz:
https://doaj.org/article/93511c23925244a89aa8795dad1b493f
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 2, Pp 31-42 (2017)
We have studied the effect of chromium disilicide and titanium nitride nanoparticles on the expression level of genes encoding important regulatory enzymes and factors (NAMPT, UPS7, E2F8, FAS/TNFSF6, TBX3, and IL13RA2) in mouse liver for evaluation o
Externí odkaz:
https://doaj.org/article/dfc6f08ed55c42f8a5102bbdca56d8aa
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 1, Pp 38-49 (2017)
We have studied the effect of hypoxia on the expression level of mRNA of the basic enzymes of pentose-phosphate cycle (G6PD, TKT, TALDO1, PGLS and RPIA) and glucose-6-phosphate isomerase (GPI) in U87 glioma cells in relation to inhibition of IRE1 (in
Externí odkaz:
https://doaj.org/article/4006cdfdcc244cbc85c50b14427b151c
Autor:
O. H. Minchenko, D. O. Tsymbal, D. O. Minchenko, O. O. Riabovol, O. O. Ratushna, L. L. Karbovskyi
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 1, Pp 11-21 (2017)
We have studied the effect of inhibition of IRE1 (inositol requiring enzyme 1), which is a central mediator of endoplasmic reticulum stress and a controller of cell proliferation and tumor growth, on hypoxic regulation of the expression of different
Externí odkaz:
https://doaj.org/article/58663eafb78e4267a48c809d5991aeaf
Autor:
O. H. Minchenko, O.V. Halkin, O. O. Riabovol, D. O. Minchenko, A. Y. Kuznetsova, O. O. Ratushna
Publikováno v:
Biotechnologia Acta, Vol 9, Iss 6, Pp 16-27 (2016)
To study the effect of glucose deprivation on the expression of genes encoding for LONP1/PRSS15 and cathepsins in U87 glioma cells in relation to inhibition of inositol requiring enzyme-1 (IRE1) was the aim of the research. It was shown that glucose
Externí odkaz:
https://doaj.org/article/0924c42fadc6493cabcbbce31930fced
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 6, Pp 52-62 (2016)
We investigated the impact of IRE1/ERN1 (inositol requiring enzyme 1/endoplasmic reticulum to nucleus signaling 1) knockdown on hypoxic regulation of the expression of a subset of proliferation and migration-related genes in U87 glioma cells. It was
Externí odkaz:
https://doaj.org/article/73dd010778674dde8b0355cab2e4f44b